Results 161 to 170 of about 167,623,224 (301)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
(A) study of atrioventricular conduction using his bundle electrogram
, 1976 의학과/석사[한글] 다극도자를 이용하여 His 속전도를 용이하게 기록하게 된 이래 심전도상의 P-R 간격은 P-A, A-H, H-V의 3 간격으로 세분할 수 있게 되었으며 따라서 부정맥과 전도장애의 연구 에 획기적인 발전을 가져왔다. 저자는 35명의 환자를 대상으로 정상 방실전도를 측정하였고 각종 부정맥을 연구분석하 였다.
김기수
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Electrocardiographic Diagnosis of Acute Myocardial Ischemia During His Bundle Pacing
Anatolian Journal of Cardiology, 2022 Leonardo Marinaccio +4 more
doaj +1 more source
Alternating bundle branch block and infra-Hisian Mobitz II block: an educational case of rapidly progressive His-Purkinje disease. [PDF]
Eur Heart J Case RepHernandez S +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
High-density mapping of his-ventricular intervals: impact of recording site and sex-specific differences. [PDF]
J Interv Card ElectrophysiolSerban T +12 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Electrophysiology Laboratory Survival Guide Part 1: Electrogram Basics, Catheters, and Basic Intervals. [PDF]
US CardiolHaloot J, Tumolo A.
europepmc +1 more source
“Selective” or “exclusive” His bundle capture
Journal of Cardiovascular Electrophysiology, 2021 Marek Jastrzębski, Karol Curila
openaire +3 more sources
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source