Results 171 to 180 of about 167,623,224 (301)

Left Bundle Branch Area Pacing in Heart Failure: A Physiological Alternative to Conventional Biventricular Cardiac Resynchronization Therapy and a Step Towards Personalized Device Therapy. [PDF]

J Pers Med
Koniari I, Gerakaris A, Kapsali E, Kanellopoulos S, Xygka G, Katsea A, Petropoulou E, Mavromati A, Koros R, Leventopoulos G, Perperis A, Kollias G, Davlouros P.   +12 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

ECG challenge: a narrow clue in a wide QRS tachycardia. [PDF]

Eur Heart J Case Rep
Nogami A, Usui R, Uno K.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

An unwanted left bundle branch block: The proteus-unveiling of his bundle pacing

HeartRhythm Case Reports
Mirco Lazzeri, MD, Michele Bertelli, MD, Alessandro Carecci, MD, Andrea Angeletti, MD, Matteo Ziacchi, MD, Mauro Biffi, MD   +5 more
doaj   +1 more source

Bundle branch re-entry ventricular tachycardia mimicking outflow-tract tachycardia: a case report. [PDF]

Eur Heart J Case Rep
Tran KD, Brome PVC, Bui DT, Nguyen NM, Lin CY.   +4 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Left bundle branch area pacing in children: a systematic review and meta-analysis of feasibility, safety, and outcomes. [PDF]

Front Cardiovasc Med
Leung HT, Tsao S, Wong WH, Cheung YF, Kwok SY.   +4 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

What is the mechanism of chronic threshold elevation after His-bundle pacing? A histopathological case report suggesting the involvement of fibrin fibrosis. [PDF]

Eur Heart J Case Rep
Baba K, Sakamoto S, Irishio M, Kataoka T, Fukuda D.   +4 more
europepmc   +1 more source