Results 161 to 170 of about 70,917 (350)

Atrioventricular Delay Optimization in His-Optimized Cardiac Resynchronization Therapy: A Case Report. [PDF]

Clin Case Rep
Nguyen Quang M, Kieu Ngoc D, Nguyen Khac Le S, Tran Le Uyen P, Nguyen Tri T.   +4 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Atrioventricular Junction Ablation with High-Definition Recording of Atrioventricular Node Potential. [PDF]

J Cardiovasc Dev Dis
Matteucci A, Maggio E, Dardani D, Russo M, Galeazzi M, Nardi F, Fedele S, Pandozi C, Colivicchi F.   +8 more
europepmc   +1 more source

Two preferential conducting pathways within the bundle of His of the dog heart.

The Japanese Journal of Physiology, 1975
J. Alanís, D. Benítez
semanticscholar   +1 more source

Extraction of His Bundle Pacing Lead: More Difficult than Coronary Sinus Lead Extraction: An Analysis of 3897 Lead Extraction Procedures Including 27 His and 253 Coronary Sinus Lead Removals [PDF]

Paweł Stefańczyk, Wojciech Jacheć, Andrzej Kutarski, Paweł Dąbrowski, Andrzej Główniak, Dorota Nowosielecka   +5 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Highlighting the Importance of His Bundle Potential During Tachycardia and Ventricular Overdrive Pacing. [PDF]

J Arrhythm
Matsunaga-Lee Y, Egami Y, Yasumoto K, Yano M, Nishino M.   +4 more
europepmc   +1 more source

His Electrogram Alternans Reveal Dual-Wavefront Inputs Into and Longitudinal Dissociation Within the Bundle of His

Circulation, 2001
Youhua Zhang, S. Bharati, K. Mowrey, S. Zhuang, P. Tchou, T. Mazgalev   +5 more
semanticscholar   +1 more source

Left Bundle Branch Area Pacing as an alternative to His Bundle pacing for Cardiac Resynchronization Therapy: a case report. [PDF]

, 2020
Jean Yves Wielandts, Alexandre Almorad, Gabriela Hilfiker, Anaïs Gauthey, Sébastien Knecht, Mattias Duytschaever, Yves Vandekerckhove, René Tavernier, Jean Benoit le Polain de Waroux   +8 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source