Innovations in cardiac device therapy in the era of advanced rhythm management: implantable defibrillators and conduction system pacing. [PDF]
Pujol-Lopez M, Tung R, Mont L.
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Lead-Related and Procedural Outcomes of His Bundle Pacing Versus Left Bundle Branch Area Pacing in Patients Undergoing Atrioventricular Node Ablation: A Systematic Review and Meta-Analysis. [PDF]
Gamarra-Valverde NN +5 more
europepmc +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
cordage bandolier with attached perfume bundle
Rope knotted at equal intervals ended with colored raffia tassels and a black colored perfume bundle84.0 cmCordage bandolier, with attached perfume bundle. This bandolier was secured in trade from Albert Robinson, an Omaha Indian dance of Macy, Nebraska,
Omaha
core
Paroxysmal atrioventricular block as an initial presentation of bicuspid aortic valve calcification: a case report. [PDF]
Lee JS, Kim JB, Kim HJ, Shim J.
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Ablation of a Para-Hisian Accessory Pathway from the Non-coronary Cusp: A Case Report. [PDF]
Marins M, Essebag V, Bernier M.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Atrial Tachycardia and Bundle Branch Re-Entry Ventricular Tachycardia With Similar QRS Complex Morphology. [PDF]
Nam GB.
europepmc +1 more source

