Results 241 to 250 of about 167,623,224 (301)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Conduction system vs. biventricular pacing in heart failure with reduced ejection fraction: a meta-analysis of randomized controlled trials. [PDF]

Europace
Karakasis P, Vlachos K, Siontis KC, Cano Ó, Tzeis S, Strik M, Pamporis K, Leventopoulos G, Antoniadis AP, Jaïs P, Burri H, Fragakis N.   +11 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Implantation of cardiac resynchronization therapy defibrillator with left bundle branch pacing in a patient with mirror-image dextrocardia: a case report. [PDF]

Front Cardiovasc Med
Yi H, Li J, Han H, Bao Y.
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Tachycardia-dependent left-bundle branch block misdiagnosed as ischaemia: a case report. [PDF]

Br J Cardiol
Rafi S, Nazir K, Nazir T, Ahmed I, Ahmed W, Chughtai AW, Ahmed A, Muhammad F, Noeman A, Ahmed U.   +9 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Conduction system pacing for cardiac resynchronization therapy: a systematic review. [PDF]

Europace
Fotos G, Ktenopoulos N, Vlachos K, Christou A, Agelaki M, Apostolos A, Samaras A, Luermans J, Vernooy K, Tsioufis K, Toutouzas K, Linz D, Boveda S.   +12 more
europepmc   +1 more source

Fasciculoventricular Pathway Mimicking Wolff-Parkinson-White Syndrome: A Delta Wave That Should Not Be Ablated. [PDF]

JACC Case Rep
Hayashi T.
europepmc   +1 more source

Seamless Transition Between Narrow- and Wide-QRS Tachycardia Revealing Double Tachycardia. [PDF]

JACC Case Rep
Ahn H, Lee JH.
europepmc   +1 more source