High-resolution 3D visualization of human hearts with emphases on the cardiac conduction system components-a new platform for medical education, mix/virtual reality, computational simulation. [PDF]
Chen W+13 more
europepmc +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Unusual left-sided variant orientation of the slow conduction zone in adenosine-sensitive atrial tachycardia. [PDF]
Arai S+4 more
europepmc +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Regional glucose consumption and glycogen measurements in rat AV node and His bundle
Keith G. Lurie+3 more
openalex +1 more source
Different levels of recruitment during conduction system pacing. [PDF]
van Koll J+3 more
europepmc +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Case report: orthodromic atrioventricular re-entrant tachycardia with left lateral accessory pathway-smart diagnosis with a smart device. [PDF]
Wiederkehr CM+3 more
europepmc +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki+2 more
wiley +1 more source