Results 31 to 40 of about 55,713 (262)
Clinical Case Reports, 2018 Key Clinical Message QRS narrowing during permanent His‐bundle pacing is primarily thought to result from longitudinal dissociation within the His bundle.
Nishant Verma, Bradley P. Knight
doaj +1 more source
CLINICAL USE OF HIS BUNDLE PACING
Nihon Naika Gakkai Zasshi, 1976 His束心電図記録に際して重要なことは, His東電位(H)のvalidationである.とくにHis-Purkinje系の伝導時間(HV)の定量的測定にはHのvalidationが必須である. Hのvalidationの方法としてHis束ペーシングが有用である. HとRB (右脚電位)の鑑別, His束内プロック時のH′(distal H)とRBの鑑別にはHis束ペーシングが有力である.われわれは左軸偏位を伴う右脚ブロック(RBBB+LAD)4例,房室ブロック6例, His束内ブロック1例, Wolff-Parkinson-White (WPW)症候群8例を含む30例でHis束心電図記録と同時にHis束ペーシングを行ない,その有用性を確認した.正常者群ではHis束ペーシング中 ...
Shigeru MOCHIZUKI +7 more
openaire +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FIRST EXPERIENCE OF DIRECT CONSTANT HIS BUNDLE PACING
Медицинский вестник Юга России, 2016 Objective: to study electrophysiological parameters and clinical results of direct constant His bundle pacing (HBP). Materials and methods: we examined 36 patients, divided into 2 equal groups (of 18 patients) according to the type of pacing.
G. V. Chudinov +7 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
AN INHERITANCE OF IDIOPATHIC CARDIAC CONDUCTION DISORDERS
Российский кардиологический журнал, 2014 Aim. To study relationship of idiopathic atrioventricular and intravenricular disorders of cardiac conductivity with mononucleotide polymorhism (MNP) A/G gene TBX5. Material and methods.
S. S. Tretyakova +6 more
doaj +1 more source
Special Issue: “Biophysics, Arrhythmias and Pacing”
Biology, 2023 Cardiac pacing technologies have been implemented during the last few decades, including leadless pacemakers and pacing of the conduction system, such as His bundle pacing and left bundle branch area pacing [...]
Matteo Bertini
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source