Results 181 to 190 of about 23,310 (265)

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

What is Balance? A Vital Mechano-Regulation Paradigm. [PDF]

Open Mind (Camb)
Wilkinson NM.
europepmc   +1 more source

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

Interdisciplinary Medicine, EarlyView.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou, Jing Lin, Yu Chen, Jiaqi Zhao   +3 more
wiley   +1 more source

Second law analysis of Casson Darcy-Forchheimer flow in two-phase nanomaterials with solar radiation and microbial cells using Homann mixed convection modeling. [PDF]

Discov Nano
Kashif AN, Zaheer KB, Saeed AM, Liu H.
europepmc   +1 more source

Ultra‐High Frequency Ultrasound Imaging and Quantification of Microvascular Flow in Xenograft Renal Cell Carcinoma in an Avian Chorioallantoic Membrane Model

Journal of Ultrasound in Medicine, EarlyView.
Patient‐derived xenograft (PDX) tumor models initiated in avian chorioallantoic membranes (CAM) are under investigation to evaluate the effectiveness of therapeutic options with the objective of personalizing treatments. CAM PDXs paired with ultra‐high frequency ultrasound (UHFUS) imaging could potentially constitute prospective high throughput assays ...
Sara Mar, Emmanuel Chérin, Justin Xu, David E. Goertz, Hon S. Leong, Christine E.M. Demore   +5 more
wiley   +1 more source

Simulated Root Exudation Gradient Reveals Dosage‐Dependent Carbon Sequestration in Desertification Ecosystems

Land Degradation &Development, EarlyView.
ABSTRACT Root exudates serve as a key driver for the restoration of soil organic carbon (SOC), particularly in aeolian desertification ecosystems where aboveground litter retention is limited. While Salix cupularis is widely planted as an effective pioneer shrub for ecological rehabilitation on the Qinghai‐Tibet Plateau, how the quantity of its root ...
Ran Xue, Xuemei Fang, Dongming Chen, Fei Yan, Aomei Jia, Zhouwen Ma, Yongheng Gao, Jiqiong Zhou, Jian Zhang, Lin Liu   +9 more
wiley   +1 more source

The Longitudinal Mediating Role of Academic Buoyancy Between Academic Self-Efficacy and Academic Burnout Among Junior High School Students: A Cross-Lagged Study. [PDF]

Behav Sci (Basel)
Ye L, Xie Y, Ye B.
europepmc   +1 more source

Bed‐level tools for monitoring erosion and accretion patterns: Flume validation and field testing

Limnology and Oceanography: Methods, EarlyView.
Abstract Monitoring short‐term changes in surface sediment elevation is fundamental to understanding erosion, transport, and deposition dynamics in shallow coastal environments. However, commonly used field approaches, such as horizontal markers, sediment erosion tables, subsurface sediment plates, or erosion pins, are not always cross‐validated under ...
Lucía Rodríguez‐Arias, Inés Mazarrasa, Beatriz Marin‐Diaz, Teresa Alcoverro, Barbara Ondiviela, Jordi F. Pagès, Eduardo Infantes   +6 more
wiley   +1 more source

The Potential of Horizontal Wells for Aquifer Storage and Recovery in Saline Aquifers. [PDF]

Ground Water
Kreipl S, Bakker M, van Breukelen BM.
europepmc   +1 more source

Diffraction‐Free Natural Optical Skyrmions and Their Subwavelength Confinement Around Vortices

Laser &Photonics Reviews, EarlyView.
ABSTRACT Diffraction causes waves to spread out as they propagate freely. The tighter the lateral confinement, the faster the spreading. Past research on how to suppress diffraction has been based on wave engineering and has led so far to idealized waves that, in real settings, eventually diffract.
Nilo Mata‐Cervera, Deepak K. Sharma, Ramon Paniagua‐Dominguez, Yijie Shen, Miguel A. Porras   +4 more
wiley   +1 more source