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Interscalene Brachial Plexus Block with Liposomal Bupivacaine versus Standard Bupivacaine with Perineural Dexamethasone: A Noninferiority Trial

Anesthesiology, 2022
Background: The interscalene nerve block provides analgesia for shoulder surgery. To extend block duration, provide adequate analgesia, and minimize opioid consumption, the use of adjuvants such as dexamethasone as well as the application of perineural ...
David H. Kim   +14 more
semanticscholar   +1 more source

Comparison of Liposomal Bupivacaine and Conventional Local Anesthetic Agents in Regional Anesthesia: A Systematic Review

Anesthesia and Analgesia, 2021
BACKGROUND: Pain is one of the most common adverse events after surgery. Regional anesthesia techniques are effective for pain control but have limited duration of action. Liposomal bupivacaine is a long-acting formulation of bupivacaine. We conduct this
Zhao-Sheng Jin   +4 more
semanticscholar   +1 more source

Clinical Effectiveness of Liposomal Bupivacaine Administered by Infiltration or Peripheral Nerve Block to Treat Postoperative Pain.

Anesthesiology, 2020
The authors provide a comprehensive summary of all randomized, controlled trials (n = 76) involving the clinical administration of liposomal bupivacaine (Exparel; Pacira Pharmaceuticals, USA) to control postoperative pain that are currently published ...
B. Ilfeld, J. Eisenach, R. Gabriel
semanticscholar   +1 more source

Liposomal Bupivacaine Interscalene Nerve Block in Shoulder Arthroplasty is Not Superior to Plain Bupivacaine: A Double Blinded Prospective Randomized Control Trial.

Journal of shoulder and elbow surgery, 2020
INTRODUCTION Interscalene brachial plexus blocks are a common modality utilized to provide adjunctive pain relief with shoulder replacement surgery. In 2018 the Federal Drug Administration approved the use liposomal bupivacaine (LB) for such nerve blocks.
S. J. Hattrup   +6 more
semanticscholar   +1 more source

Predicting the Density of Bupivacaine and Bupivacaine-Opioid Combinations

Anesthesia & Analgesia, 2002
Manipulating the density of local anesthetic solutions by using a simple formula may be clinically useful in producing optimal density solutions for spinal anesthesia under a variety of clinical conditions.
Stephen P, Hallworth   +2 more
openaire   +2 more sources

The clinical effectiveness of epidural bupivacaine, bupivacaine with lidocaine, and bupivacaine with fentanyl for labor analgesia

Journal of Clinical Anesthesia, 1991
To examine the efficacy of bupivacaine alone and in combination with lidocaine or fentanyl for epidural analgesia during labor.Randomized, single-blind study.Labor and delivery unit at a university medical center.Forty-five primiparas requesting epidural analgesia.Following epidural placement at L3-4 interspace, patients received either bupivacaine 0.5%
R S, Sinatra   +2 more
openaire   +2 more sources

Analgesic Effectiveness of Liposomal Bupivacaine versus Plain Local Anesthetics for Abdominal Fascial Plane Blocks: A Systematic Review and Meta-analysis of Randomized Trials

Anesthesiology
Background: Liposomal bupivacaine is reported to prolong the duration of analgesia when used for abdominal fascial plane blocks compared to plain local anesthetics; however, evidence from randomized trials is mixed. This meta-analysis aims to compare the
N. Hussain, Jarod Speer, F. Abdallah
semanticscholar   +1 more source

A COMPARISON OF BUPIVACAINE AND ALKALINIZED BUPIVACAINE IN BRACHIAL PLEXUS ANESTHESIA

Anesthesia & Analgesia, 1987
To define the effect of alkalinization of bupivacaine 0.5% in subclavian perivascular brachial plexus blockade, the time to onset, time to peak effect, and 6-hour regression of sensory and motor blockade were determined. Sixty physical status ASA I and II patients were randomly allocated to one of two groups and a double-blind design was used: group I (
M D, Bedder, R, Kozody, D B, Craig
openaire   +2 more sources

Recovery quality of transversus abdominis plane block with liposomal bupivacaine after cesarean delivery: A randomized trial.

Journal of clinical anesthesia
STUDY OBJECTIVE This study aimed to investigate the effect of liposomal bupivacaine in transversus abdominis plane block (TAP) on recovery quality after cesarean delivery. DESIGN A randomized trial.
Henghua Liu   +4 more
semanticscholar   +1 more source

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