Results 101 to 110 of about 62,498 (301)

Engineering ApoE‐Mimetic HDL‐Like Nanoparticles for Glioblastoma‐Targeted Theranostics

Small Methods, EarlyView.
An ApoE‐mimetic peptide enables the stable formation of sub‐30 nm HDL‐like nanoparticles (ApoEm‐PLP) that simultaneously engage multiple lipoprotein receptors. This multivalent receptor interaction facilitates the transport of ApoEm‐PLP into brain and enhances targeted delivery of ApoEm‐PLP to glioblastoma, resulting in uniform intratumoral porphyrin ...
Hanyi Weng, Rick Wentao Cui, Ling Xi Gong, Ashley Qian, Lili Ding, Nahyun Kwon, Yiming Yang, Yulin Mo, Tiffany Ho, Madeline K. Brown, Maneesha Amrita Rajora, Juan Chen, Gang Zheng   +12 more
wiley   +1 more source

Single‐dose enflicoxib versus a 7‐day course of firocoxib for postoperative pain control in dogs undergoing orthopaedic surgery: A multicentre, randomised, masked, non‐inferiority study

Veterinary Record, EarlyView.
Abstract Background Perioperative analgesia is essential in dogs undergoing orthopaedic surgery, and enflicoxib's long duration makes single‐dose administration attractive. Methods A prospective, multicentre, randomised, masked trial compared enflicoxib (8 mg/kg) given 24 hours before surgery with firocoxib (5 mg/kg) given daily for 7 days. Two hundred
Marta Salichs, José I. Redondo, Anabel Blasco‐Moreno, Llorenç Badiella, Josep Homedes   +4 more
wiley   +1 more source

Chronic Disease and Disability in the United States: Trends, Inequities, and Imperatives for Policy Reform

The Milbank Quarterly, EarlyView.
Policy Points Position Universal, High‐Quality Education as a Foundational Public Health Strategy. Long‐term health and life expectancy in the United States are shaped more by educational attainment than by any other single factor. Disparities in access to early childhood, K‐12, and higher education perpetuate cycles of chronic disease, economic ...
ALI H. MOKDAD, LAURA DWYER‐LINDGREN, CHRISTOPHER J.L. MURRAY   +2 more
wiley   +1 more source

Donepezil reverses buprenorphine-induced central respiratory depression in anesthetized rabbits

Biological Research, 2009
Buprenorphine is a mixed opioid receptor agonist-antagonist used in acute and chronic pain management. Although this agent's analgesic effect increases in a dose-dependent manner, buprenorphine-induced respiratory depression shows a marked ceiling effect
SHIGEKI SAKURABA, MIKI TSUJITA, HIROFUMI ARISAKA, JUNZO TAKEDA, KAZUICHI YOSHIDA, SHUN-ICHI KUWANA   +5 more
doaj  

Buprenorphine: a guide for nurses. [PDF]

, 2009
[Note: this publication is no longer available on the SAMHSA website. It is here for archival purposes]. This guide is intended to provide nurses with general information about buprenorphine products—Suboxone® (buprenorphine and naloxone) and Subutex®

core  

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

Addiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall, Lakshmi Ganapathi, Mihili P. Gunaratne, Aylur K. Srikrishnan, Conjeevaram K. Vasudevan, Santhanam Anand, Sunil S. Solomon, Shruti H. Mehta, Gregory M. Lucas   +8 more
wiley   +1 more source

Does perceived stigma impact opioid use disorder treatment uptake? A cross-sectional secondary analysis of buprenorphine engagement among syringe service program participants

Addiction Science & Clinical Practice
Introduction Buprenorphine is an effective medication for opioid use disorder (OUD) treatment; however, stigma surrounding substance use may deter individuals from seeking treatment and contribute to lower engagement once treatment is initiated.
Bailey Campbell, Lindsey R. Riback, Juan Gatica Portillo, Stephanie Maricic, Aaron D. Fox   +4 more
doaj   +1 more source

Am J Prev Med [PDF]

At least 2.3 million people in the U.S. have an opioid use disorder, less than 40% of whom receive evidence-based treatment. Buprenorphine used as part of medication-assisted treatment has high potential to address this gap because of its approval for ...

core  

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Opioid-induced constipation: rationale for the role of norbuprenorphine in buprenorphine-treated individuals

Substance Abuse and Rehabilitation, 2016
Lynn R Webster,1 Michael Camilleri,2 Andrew Finn3 1PRA Health Sciences, Salt Lake City, UT, 2Mayo Clinic Rochester, MN, 3BioDelivery Sciences, Inc., Raleigh, NC, USA Abstract: Buprenorphine and buprenorphine–naloxone fixed combinations are ...
Webster LR, Camilleri M, Finn A
doaj