Results 81 to 90 of about 11,287 (253)

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

Equine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla, José I. Redondo, Polly M. Taylor, Luis Domenech, Javier Doménech, Gordon Mark Johnston, Regula Bettschart‐Wolfensberger   +6 more
wiley   +1 more source

J Subst Abuse Treat [PDF]

Background:Telemedicine-delivered buprenorphine (tele-buprenorphine) can potentially increase access to buprenorphine for patients with opioid use disorder (OUD), especially during the COVID-19 pandemic, but we know little about use in clinical care ...

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Addressing in‐hospital substance use: A bioethical evaluation of two possible approaches

Journal of Hospital Medicine, EarlyView.
Abstract Up to 40% of patients with substance use disorder report using non‐prescribed drugs when hospitalized. In‐hospital substance (IHSU) use is associated with poor outcomes and raises safety concerns for healthcare providers. Despite its prevalence, little guidance exists regarding best practices in responding to IHSU.
John C. Messinger, Taylor Baisey, Johanna Sluser, Benjamin A. Barsky, Marlene Martin, Leslie W. Suen   +5 more
wiley   +1 more source

Practices and Outcomes Associated With Sublingual Buprenorphine Use in a Critically Ill Population

Critical Care Explorations
IMPORTANCE:. Buprenorphine for opioid use disorder (OUD) is commonly used in the outpatient setting with increasing use in hospitalized patients. However, there is limited literature describing its use in critically ill populations. OBJECTIVES:.
Denis J. Vanini, PharmD, BCCCP, Jenna M. Corvelli, PharmD, BCCCP, Kaylee M. Maynard, PharmD, BCCCP, Stephen H. Rappaport, PharmD, BCCCP, Gina Grasso, PharmD, Raquel Jones, PharmD, BCPS, Nicole M. Acquisto, PharmD, FASHP, FCCM, FCCP, BCCCP, Rachel F. Schult, PharmD, DABAT   +7 more
doaj   +1 more source

Low-dose naloxone provides an abuse-deterrent effect to buprenorphine

, 2015
Lynn R Webster,1 Michael D Smith,1 Cemal Unal,2 Andrew Finn3 1PRA Health Sciences, Salt Lake City, UT, USA; 2Biometrical Solutions LLC, Raleigh, NC, USA; 3BioDelivery Sciences International, Inc., Raleigh, NC, USA Abstract: In developmental research ...
Unal C, Finn A, Smith MD, Webster LR
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The Efficacy of Buprenorphine in Preoperative and Postoperative Patients: A Literature Review [PDF]

Although research suggests that less than half of individuals who have surgical procedures report effective postoperative pain alleviation, the majority of patients endure acute postoperative discomfort. To lessen and manage postoperative pain, a variety
Patel, Keyur, Jermyn, Richard, Lee, Paul, Patel, Kunnal, Witherspoon, Jessica   +4 more
core   +1 more source

Postoperative Buprenorphine Discontinuation in Continuously Treated Buprenorphine Patients: A Population Cohort Study [PDF]

, 2021
Sudden discontinuation of buprenorphine in opioid use disorder increases the risk of relapse and overdose. The thesis objective was to understand patient, procedural, opioid treatment-related and health service use factors associated with discontinuing ...
Hauck, Tanya Sabrina
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Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Buprenorphine treatment in pregnancy: less distress to babies.

, 2010
Pres release by National Institute on Drug Abuse, United States: NIH study compares buprenorphine to methadone in opioid addicted pregnant women Babies born to women addicted to opioids fare better when their mothers are treated with either the ...

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