Results 61 to 70 of about 11,287 (253)
PLoS ONEBuprenorphine in an extended-release formulation intended for use in laboratory subjects is frequently administered to rats to provide extended analgesia without repeated handling.
Christina M Larson +5 more
doaj +1 more source
Colon constipation in horses after sustained-release buprenorphine administration. [PDF]
, 2018 OBJECTIVE To investigate the pharmacological profile and side effects of buprenorphine administered as a sustained-release formulation in horses. STUDY DESIGN Pilot trial.
Spadavecchia, Claudia +2 more
core +1 more source
Advanced Science, EarlyView.Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li +8 more
wiley +1 more source
Methadone and buprenorphine effects on driving abilities [PDF]
, 2020 Driving under the influence of drugs and alcohol are major contributors to the high frequency of road traffic crashes globally. Methadone and buprenorphine are among the twenty drugs most frequently detected in apprehended drivers suspected of drug ...
Strand, Maren Cecilie
core +3 more sources
Animal Models and Experimental Medicine, EarlyView.A refined murine model of advanced ovarian cancer was established by comparing localized preperitoneal implantation and intraperitoneal injection of OVCAR‐3Luc cells. While localized implantation showed limited tumor persistence, intraperitoneal delivery with BME produced sustained diffuse dissemination confirmed by BLI and histology, providing a ...
M. Teresa Perelló‐Trias +5 more
wiley +1 more source
Animal stroke models and outcome evaluation: A review
Animal Models and Experimental Medicine, EarlyView.Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba +2 more
wiley +1 more source
Buprenorphine, oxycodone, hydrocodone, and methadone mortality in the United States (2010‒2017)
Journal of the American College of Emergency Physicians OpenObjective Opioid overdose survivors present to emergency departments (EDs) and many EDs have developed programs to initiate buprenorphine. The impact of the increasing use of buprenorphine in ED and by other providers is unknown while opioid mortality ...
Karilynn M. Rockhill +6 more
doaj +1 more source
Buprenorphine in acute pain: a partial agonist or not? (Letter)
, 2019 Editor—There currently exists confusion regarding the status of buprenorphine as a partial agonist of the μ-opioid receptor (MOP), particularly in the setting of acute pain management for opioid-naïve patients.1 Buprenorphine, a semi-synthetic derivative
White, L +4 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen +17 more
wiley +1 more source