Results 41 to 50 of about 62,498 (301)
Annals of Medicine, 2023 Background: At the start of the pandemic, relaxation of buprenorphine prescribing regulations created an opportunity to create new models of medications for opioid use disorder (MOUD) delivery and care.
Edward Suarez +9 more
doaj +1 more source
Buprenorphine in acute pain: a partial agonist or not? (Letter)
, 2019 Editor—There currently exists confusion regarding the status of buprenorphine as a partial agonist of the μ-opioid receptor (MOP), particularly in the setting of acute pain management for opioid-naïve patients.1 Buprenorphine, a semi-synthetic derivative
White, L +4 more
core +1 more source
High buprenorphine-related mortality is persistent in Finland [PDF]
, 2018 Sublingual buprenorphine is used in opioid maintenance treatment but buprenorphine is also widely abused and causes fatal poisonings. The aim of this study was to investigate buprenorphine-positive fatalities in order to gain novel information on the ...
Ojanpera, Ilkka +2 more
core +1 more source
Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
Addiction Science & Clinical PracticeBackground Increases in prescribing of buprenorphine for pain or opioid use disorder (OUD) have led to concerns regarding its interactions with other drugs used concomitantly and risk of adverse clinical outcomes. Objective To synthesize current evidence
Jude Uche Eze +3 more
doaj +1 more source
Advanced Science, EarlyView.A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source
Advanced Science, EarlyView.A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li +9 more
wiley +1 more source
A Case Study of Pain Management at End-of-Life for a Patient on High-Dose Buprenorphine
Journal of Patient Experience, 2022 In Australia, high-dose sublingual buprenorphine and long-acting injectable buprenorphine are available. High-dose buprenorphine is used predominantly in the setting of opioid use disorder and has a role in chronic pain.
Naomi T Katz +5 more
doaj +1 more source
Advanced Science, EarlyView.Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang +10 more
wiley +1 more source
National opioid pharmacotherapy statistics annual data collection 2012 [PDF]
, 2013 On a snapshot day in 2012, almost 47,000 clients received pharmacotherapy treatment for their opioid dependence at 2,226 dosing points around Australia, this report finds.SummaryAlmost 47,000 Australians received pharmacotherapy treatment for their ...
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