Stigma as a fundamental hindrance to the United States opioid overdose crisis response. [PDF]
, 2019 Alexander Tsai and co-authors discuss the role of stigma in responses to the US opioid ...
Barnett, Michael L +9 more
core +2 more sources
Neurobehavioral consequences of chronic intrauterine opioid exposure in infants and preschool children: a systematic review and meta-analysis [PDF]
, 2014 <b>Background</b><p></p> It is assumed within the accumulated literature that children born of pregnant opioid dependent mothers have impaired neurobehavioral function as a consequence of chronic intrauterine opioid use.<p>&
A Baldacchino +86 more
core +15 more sources
Improving Uptake of Emergency Department-initiated Buprenorphine: Barriers and Solutions
Western Journal of Emergency Medicine, 2022 Emergency departments (ED) are increasingly providing buprenorphine to persons with opioid use disorder. Buprenorphine programs in the ED have strong support from public health leaders and emergency medicine specialty societies and have proven to be ...
Timothy D. Kelly +4 more
doaj +1 more source
Lack of analgesic efficacy in female rats of\ud the commonly recommended oral dose of\ud buprenorphine [PDF]
, 2006 Previous work in our laboratory showed that the recommended oral dose of buprenorphine (0.5 mg/kg) was not as effective\ud as the standard therapeutic subcutaneous dose for postoperative analgesia in male Long-Evans (hooded) and Sprague-Dawley (albino ...
DiPirro, Dr. Jean M. +4 more
core
Buprenorphine added on brief cognitive behavioral therapy for treatment of methamphetamine use disorder [PDF]
, 2018 Background: Methamphetamine (MA) use remains a major public health concern around the world. Recent findings suggest that buprenorphine may be helpful for cocaine use reduction. Moreover, animal studies described reduced dopamine peak effect following MA
Dean AJ +10 more
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Dense Nanofibrillar Collagen–Silica Hybrids with High Strength and ECM‐Mimetic Tissue Integration
Advanced Functional Materials, EarlyView.Dense nanofibrillar collagen–silica hybrids are engineered by synchronizing collagen fibrillogenesis with silica condensation, producing printable scaffolds that unexpectedly approach native extracellular matrix organization and strength. These cell‐free constructs guide endogenous cell‐infiltration, enable localized matrix remodeling, and integrate ...
Norein Norein +7 more
wiley +1 more source
A Guide to Expanding the Use of Buprenorphine Beyond Standard Initiations for Opioid Use Disorder
Drugs in R&D, 2023 Buprenorphine has become an important medication in the context of the ongoing opioid epidemic. However, complex pharmacologic properties and varying government regulations create barriers to its use.
James C. Miller +4 more
doaj +1 more source
Advanced Functional Materials, EarlyView.We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu +7 more
wiley +1 more source
Low-dose buprenorphine initiation during pregnancy: a case report
AJOG Global ReportsBuprenorphine is recommended for pregnant patients with opioid use disorder. Traditional buprenorphine initiation requires moderate withdrawal symptoms to prevent precipitating withdrawal.
Shivania Reddy, BSc +1 more
doaj +1 more source