Results 151 to 160 of about 40,708 (270)

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni   +9 more
wiley   +1 more source

Weight‐Reduction and Safety Profile of Once‐Weekly Non‐Comparable Biotherapeutic Subcutaneous Semaglutide Among People With Obesity: A Real‐World Retrospective Study

open access: yesHealth Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Semaglutide, a once‐weekly injectable glucagon‐like peptide, showed double‐digit weight reduction with an acceptable safety profile in clinical trials and real‐world studies. The efficacy and safety of non‐comparable biotherapeutic (NCB) semaglutide are not adequately reported. Our study aimed to assess the weight reduction
Md Rakibul Hasan   +2 more
wiley   +1 more source

Olanzapine Attenuates Cue-elicited Craving for Tobacco

open access: yes, 2004
Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures
Hutchinson, Kent E   +5 more
core  

Tobacco Cessation Treatments Among Young Adult Smokers [PDF]

open access: yes, 2007
Summarizes a study of differences between younger and older adult smokers in their motivations and attempts to quit and their use of smoking cessation treatments.
Amy Sporer   +5 more
core  

A Meta-Analysis of the Efficacy of Bupropion Sustained-Release for Smoking Cessation in Heavy Smokers

open access: yesImpulse: The Premier Undergraduate Neuroscience Journal, 2017
Cigarette smoking damages just about every organ in the body and reduces overall health. Even with the prevalence of accessible nicotine replacement therapies and behavioral counseling, there remains a need for alternative therapies to improve the odds ...
Adrian Paszek
doaj  

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 238-271, January 2026.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg   +3 more
wiley   +1 more source

Methamphetamine‐Associated Pulmonary Arterial Hypertension: Impact, Mechanisms, and a Framework for Management

open access: yesPulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Methamphetamine‐associated pulmonary arterial hypertension (Meth‐PAH) is an increasingly prevalent but understudied subtype of Group 1 pulmonary arterial hypertension (PAH). While most prevalent in the Western United States, its reach continues to expand with the evolving global methamphetamine epidemic.
Namita Sood   +4 more
wiley   +1 more source

The Response of Ventral Tegmental Area Dopaminergic Neurons to Bupropion: Excitation or Inhibition?

open access: yesBasic and Clinical Neuroscience, 2019
Introduction: Antidepressants can modulate brain monoamines by acting on pre-synaptic and postsynaptic receptors. Autoreceptors can reduce the monoamines effect on the somatodendritic or pre-synaptic regions despite its postsynaptic counter effects.
Shirin Sadighparvar   +4 more
doaj  

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