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Holistic Management of Adult ADHD with a History of Addiction: Emphasis on Low-Addiction-Risk Psychopharmacotherapy. [PDF]
J Clin MedŻełabowski K +11 more
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Drug Intelligence & Clinical Pharmacy, 1984
Bupropion is a trimethylated monocyclic phenylaminoketone that is an effective antidepressant in humans. It neither is sedating, anticholinergic, nor cardiotoxic. Its mechanism of action may be related to dopamine, but remains uncertain at this time.Clinical trials comparing bupropion 300–750 mg/d with placebo show it to be superior to placebo in ...
Dufresne, R., Weber, S., Becker, R. E.
openaire +3 more sources
Bupropion is a trimethylated monocyclic phenylaminoketone that is an effective antidepressant in humans. It neither is sedating, anticholinergic, nor cardiotoxic. Its mechanism of action may be related to dopamine, but remains uncertain at this time.Clinical trials comparing bupropion 300–750 mg/d with placebo show it to be superior to placebo in ...
Dufresne, R., Weber, S., Becker, R. E.
openaire +3 more sources
2016
Bupropion hydrochloride is a norepinephrine-dopamine disinhibitor (NDDI) approved for the treatment of depression and smoking cessation. Bupropion is a trimethylated monocyclic phenylaminoketone second-generation antidepressant, which differs structurally from most antidepressants, and resides in a novel mechanistic class that has no direct action on ...
S R, Khan +6 more
openaire +2 more sources
Bupropion hydrochloride is a norepinephrine-dopamine disinhibitor (NDDI) approved for the treatment of depression and smoking cessation. Bupropion is a trimethylated monocyclic phenylaminoketone second-generation antidepressant, which differs structurally from most antidepressants, and resides in a novel mechanistic class that has no direct action on ...
S R, Khan +6 more
openaire +2 more sources
Bupropion and Bupropion Analogs as Treatments for CNS Disorders
2014Bupropion, introduced as an antidepressant in the 1980s, is also effective as a smoking cessation aid and is beneficial in the treatment of methamphetamine addiction, cocaine dependence, addictive behaviors such as pathological gambling, and attention deficit hyperactivity disorder. (2S,3S)-hydroxybupropion is an active metabolite of bupropion produced
F Ivy, Carroll +5 more
openaire +2 more sources