Results 51 to 60 of about 47,532 (242)

Using the Social-Local-Mobile App for Smoking Cessation in the SmokeFreeBrain Project: Protocol for a Randomized Controlled Trial [PDF]

open access: yes, 2018
Background: Smoking is considered the main cause of preventable illness and early deaths worldwide. The treatment usually prescribed to people who wish to quit smoking is a multidisciplinary intervention, combining both psychological advice and ...
Bamidis, Panagiotis D.   +10 more
core   +3 more sources

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg   +3 more
wiley   +1 more source

A randomized clinical trial on the effects of bupropion and buprenorphine on the reduction of methamphetamine craving

open access: yesTrials, 2019
BackgroundThe purpose of this study was to compare the effect of 300 mg of bupropion and 8 mg of buprenorphine per day on the treatment of methamphetamine withdrawal cravings over a 2-week treatment interval.MethodSixty-five methamphetamine-dependent men
J. Ahmadi, A. Sahraian, Mehdi Biuseh
semanticscholar   +1 more source

Understanding the Increasing Prevalence of Obesity in Patients With Type 1 Diabetes: Strategies for Improving Clinical Care

open access: yesObesity, EarlyView.
ABSTRACT The presence of excess weight is no longer a distinguishing feature between patients with type 1 diabetes (T1D) and those with type 2 diabetes (T2D). Obesity treatment in patients with T2D improves glycemic control and reduces or even eliminates medication burden.
Kathleen R. Ruddiman   +2 more
wiley   +1 more source

Circulating levels of proglucagon‐derived peptides are differentially regulated by the glucagon‐like peptide‐1 agonist liraglutide and the centrally acting naltrexone/bupropion and can predict future weight loss and metabolic improvements: A 6‐month long interventional study [PDF]

open access: green, 2023
Konstantinos Stefanakis   +11 more
openalex   +1 more source

Reasons for Discontinuation of Obesity Pharmacotherapy With Semaglutide or Tirzepatide in Clinical Practice

open access: yesObesity, EarlyView.
ABSTRACT Objective This study aimed to characterize the reasons for treatment discontinuation with injectable semaglutide or tirzepatide for obesity in regular clinical practice. Methods This cross‐sectional study used electronic health record data between January 2022 and December 2024 from a single integrated health system in Ohio and Florida.
Hamlet Gasoyan   +9 more
wiley   +1 more source

Nicotine-replacement therapy: A proven treatment for smoking cessation [PDF]

open access: yes, 2010
Smoking is a major cause of cardiovascular diseases, respiratory diseases and cancer. Despite the high prevalence of smokers worldwide, smokers are often neglected and not offered effective assistance with quitting their habits. In order to overcome this
Robson, Noorzurani
core   +1 more source

An Open‐Source Framework for Virtual Bioequivalence Modeling and Clinical Trial Design

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT To establish bioequivalence (BE) of a generic test formulation with respect to a reference listed drug, it is necessary to demonstrate a comparable rate and extent to which active ingredients reach the site of action. To decrease unnecessary human testing and simulate scenarios involving specific populations or challenges with recruitment or ...
Abdullah Hamadeh   +13 more
wiley   +1 more source

The Efficacy and Toxicity of Bupropion in the Elderly [PDF]

open access: yes, 2012
Bupropion is an antidepressant with excellent tolerability and few side effects or drug interactions. These characteristics suite it well for use both in the elderly and in the medically ill.
Howard, William T., M.D., M.S.   +1 more
core   +1 more source

Toxicity of Bupropion Overdose Compared With Selective Serotonin Reuptake Inhibitors

open access: yesPediatrics, 2019
Fluoxetine and escitalopram are FDA-approved prescription medications for pediatric depression but are not the only agents used. We examine adolescent overdose risks of bupropion and SSRIs.
A. Overberg   +3 more
semanticscholar   +1 more source

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