Results 141 to 150 of about 1,360,024 (265)

Global and regional disparities in the burden of disease and risk factors between pancreatitis and pancreatic cancer: a systematic analysis for the global burden of disease study. [PDF]

BMC Gastroenterol
Getu MA, Liu J, Ma L, Zhang X.
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Burden of oral diseases

Indian Journal of Dental Research, 2016
openaire   +3 more sources

Mortality rates in patients with Parkinson's disease: An analysis of the Global Burden of Disease database. [PDF]

Surg Neurol Int
Gould J, Patel S, Chaurasia B.
europepmc   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Potential effect of real-world junk food and sugar-sweetened beverage taxes on population health, health system costs and greenhouse gas emissions in New Zealand: a modelling study

BMJ Nutrition, Prevention & Health
Tony Blakely, Anja Mizdrak, Cliona Ni Mhurchu, Amanda C Jones, Nhung Nghiem, Leah Grout, Christine Cleghorn   +6 more
doaj   +1 more source

Burden of cardiovascular disease in Pakistan - insight from global burden of disease study 2019. [PDF]

BMC Cardiovasc Disord
Abdul Jabbar AB, Mansoor T, Sheikh S, Jafar TH, Hanif S, Razo C, Alam M, Rana JS, Nasir K, Hanif B, Virani SS, Minhas AMK.   +11 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The global, regional, and national burden of disease attributable to non-optimal temperatures in children. [PDF]

Transl Pediatr
Gu X, Hu M, Liu T, Uludag K, Zhou W.
europepmc   +1 more source