Results 1 to 10 of about 69,216 (297)

Alzheimer’s Disease–Thrombosis Comorbidity: A Growing Body of Evidence from Patients and Animal Models

Cells
Background/Objectives: A growing body of evidence is amassing in the literature suggesting a correlation between Alzheimer’s disease (AD) and thrombotic vascular complications, which led to the suggestive hypothesis that thrombosis may contribute to AD ...
Joanna Koch-Paszkowski, Christopher Sennett, Giordano Pula   +2 more
doaj   +1 more source

Measuring multimorbidity in hospitalised patients using linked hospital episode data: comparison of two measures

International Journal of Population Data Science, 2019
Introduction Multimorbidity is a complex and growing health challenge. There is no accepted “gold standard” multimorbidity measure for hospital resource planning, and few studies have compared measures in hospitalised patients.
Lynn Robertson, Dolapo Ayansina, Marjorie Johnston, Angharad Marks, Corri Black   +4 more
doaj   +1 more source

Effect of multimorbidity on hypertension management

Scientific Reports, 2023
Multimorbidity, the coexistence of multiple health conditions, is associated with functional decline, disability, and mortality. We aimed to investigate the effects of multimorbidity on hypertension treatment and control rates by analyzing data from the ...
Eunjeong Ji, Soyeon Ahn, Jung-Yeon Choi, Cheol-Ho Kim, Kwang-il Kim   +4 more
doaj   +1 more source

Combined Use of Gefitinib and Bevacizumab in Advanced Non-Small-Cell Lung Cancer with EGFR G719S/S768I Mutations and Acquired C797S Without T790M After Osimertinib: A Case Report and Literature Review

Current Oncology
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are effective in non-small-cell lung cancer (NSCLC) with sensitizing mutations.
Wenting Lu, Jiayi Sun, Yawan Jing, Jing Xu, Chengming Huang, Yi Deng, Panwen Tian, Yalun Li   +7 more
doaj   +1 more source

The association between multiple long‐term conditions and dementia: A UK cohort study

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Studies examining the risk of dementia in people with multimorbidity are commonly conducted in research cohorts or outside the UK. Multimorbidity has historically been associated with aging, but recent research suggests that more than half ...
Hilary Shepherd, Adam Todd, David R. Sinclair, Charlotte L. Richardson, Fiona E. Matthews, Andrew Kingston   +5 more
doaj   +1 more source

Association between multimorbidity patterns and disability among older people covered by long-term care insurance in Shanghai, China

BMC Public Health, 2021
Background Functional disability and multimorbidity are common among older people. However, little is known about the relationship between functional disability and different multimorbidity combinations.
Zijing Wang, Wenjia Peng, Mengying Li, Xinghui Li, Tingting Yang, Cancan Li, Huosheng Yan, Xianjie Jia, Zhi Hu, Ying Wang   +9 more
doaj   +1 more source

Social determinants of multimorbidity and multiple functional limitations among the ageing population of England, 2002–2015

SSM: Population Health, 2019
This study explores longitudinal relationships between material, psycho-social and behavioural social determinants of health and multimorbidity of people aged 50 years or older in England.
Leo Singer, Mark Green, Francisco Rowe, Yoav Ben-Shlomo, Karyn Morrissey   +4 more
doaj   +1 more source

Multi-omics analyses reveal biological and clinical insights in recurrent stage I non-small cell lung cancer

Nature Communications
Post-operative recurrence rates of stage I non-small cell lung cancer (NSCLC) range from 20% to 40%. Nonetheless, the molecular mechanisms underlying recurrence hitherto remain largely elusive.
Chengdi Wang, Jingwei Li, Jingyao Chen, Zhoufeng Wang, Guonian Zhu, Lujia Song, Jiayang Wu, Changshu Li, Rong Qiu, Xuelan Chen, Li Zhang, Weimin Li   +11 more
doaj   +1 more source

Prevalence and patterns of chronic non-communicable disease multimorbidity in an Indonesian adult population

Public Health of Indonesia
Background: Chronic non-communicable diseases (NCDs) are a global health challenge, with increasing prevalence of multimorbidity. Objective: This study was to examine the prevalence of chronic NCDs and their multimorbidity patterns in the Indonesian ...
Hoirun Nisa, Hari Hendarto, Femmy Nurul Akbar, Silvia Nasution, Lilik Zuhriyah   +4 more
doaj   +1 more source

Efficacy and safety of neoadjuvant targeted therapy in non-small cell lung cancer: a systematic review and meta-analysis

Systematic Reviews
Introduction Epidermal growth factor receptor (EGFR) mutations are major oncogenic drivers in non-small cell lung cancer (NSCLC), occurring in 30–50% of Asian patients. Neoadjuvant EGFR-tyrosine kinase inhibitors (EGFR-TKIs) may improve surgical outcomes
Honglin Li, Lan Yang, Jiayi Sun, Jingwen Lin, Weimin Li, Panwen Tian, Yalun Li   +6 more
doaj   +1 more source