Results 41 to 50 of about 85,807 (301)

Multiple morbidities in companion dogs: a novel model for investigating age-related disease [PDF]

, 2016
The proportion of men and women surviving over 65 years has been steadily increasing over the last century. In their later years, many of these individuals are afflicted with multiple chronic conditions, placing increasing pressure on healthcare systems.
Delignette-Muller ML, DuGoff EH, R Core Team, Treuting PM, Venables WN, Yancik R   +5 more
core   +3 more sources

Associations of Rheumatoid Arthritis Disease Activity with Frailty Over Five Years of Follow‐up

Arthritis Care &Research, Accepted Article.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis registry enrolled from 2003 to 2022 were included. The exposure was RA disease activity measured by Disease Activity Score in 28‐joints (DAS28)
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Management of tunneled-cuffed catheters in hemodialysis patients with hypotension and recurrent central venous thrombosis: A single-center retrospective cohort study

Science Progress
Objective To evaluate management strategies of tunneled-cuffed catheters (TCCs) in hemodialysis (HD) patients with hypotension and recurrent central venous thrombosis.
Jibo Sun, Hong Fan, Tianlei Cui
doaj   +1 more source

Determinants of the onset and development of multimorbidity in different subpopulations of older Chinese adults: insights from the China Health and Retirement Longitudinal Study

Annals of Medicine
Background and objectives Multimorbidity trajectories help to analyze the onset and development of multimorbidity over time and are an important public health matter.
Changcong Wang, Shutong Wang, Haitao Yu, Xinyue Zhang, Meng Zhang, Dongmei Mu   +5 more
doaj   +1 more source

Obesity subtypes and longitudinal trajectories of function over 7‐years of follow‐up: data from the Multicenter Osteoarthritis Study

Arthritis Care &Research, Accepted Article.
Background Obesity, defined by BMI ≥30kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA.
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi   +6 more
wiley   +1 more source

Sex-specific patterns and lifetime risk of multimorbidity in the general population: a 23-year prospective cohort study

BMC Medicine, 2022
Background Multimorbidity poses a major challenge for care coordination. However, data on what non-communicable diseases lead to multimorbidity, and whether the lifetime risk differs between men and women are lacking.
Premysl Velek, Annemarie I. Luik, Guy G. O. Brusselle, Bruno Ch. Stricker, Patrick J. E. Bindels, Maryam Kavousi, Brenda C. T. Kieboom, Trudy Voortman, Rikje Ruiter, M. Arfan Ikram, M. Kamran Ikram, Evelien I. T. de Schepper, Silvan Licher   +12 more
doaj   +1 more source

Secondary analysis of data on comorbidity/multimorbidity: a call for papers [PDF]

, 2015
Despite the high proportion and growing number of people with comorbidity/multimorbidity, clinical trials often exclude this group, leading to a limited evidence base to guide policy and practice for these individuals [1–5].
Fortin, Martin, Gunn, Jane, Mercer, Stewart, Smith, Susan, van den Akker, Marjan   +4 more
core   +2 more sources

Multimorbidity and complex multimorbidity in Brazilian rural workers

PLOS ONE, 2019
To estimate the prevalence of multimorbidity and complex multimorbidity in rural workers and their association with sociodemographic characteristics, occupational contact with pesticides, lifestyle and clinical condition.This is a cross-sectional epidemiological study with 806 farmers from the main agricultural municipality of the state of Espírito ...
Glenda Blaser Petarli, Monica Cattafesta, Monike Moreto Sant’Anna, Olívia Maria de Paula Alves Bezerra, Eliana Zandonade, Luciane Bresciani Salaroli   +5 more
openaire   +4 more sources

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Temporal change in multimorbidity prevalence, clustering patterns, and the association with mortality: findings from the China Kadoorie Biobank study in Jiangsu Province

Frontiers in Public Health
ObjectivesThe characteristics of multimorbidity in the Chinese population are currently unclear. We aimed to determine the temporal change in multimorbidity prevalence, clustering patterns, and the association of multimorbidity with mortality from all ...
Hao Yu, Hao Yu, Ran Tao, Jinyi Zhou, Jian Su, Yan Lu, Yujie Hua, Jianrong Jin, Pei Pei, Canqing Yu, Canqing Yu, Canqing Yu, Dianjianyi Sun, Dianjianyi Sun, Dianjianyi Sun, Zhengming Chen, Liming Li, Liming Li, Liming Li, Jun Lv, Jun Lv, Jun Lv   +21 more
doaj   +1 more source