Results 61 to 70 of about 65,300 (190)

Prone positioning does not improve outcomes of intubated patients with pneumocystis pneumonia and moderate–severe acute respiratory distress syndrome: a single-center, retrospective, observational, cohort study

open access: yesEuropean Journal of Medical Research
Background Pneumocystis pneumonia is an uncommon precipitant of acute respiratory distress syndrome and is associated with high mortality. Prone positioning ventilation has been proven to reduce mortality in patients with moderate–severe acute ...
Zhen Wang   +6 more
doaj   +1 more source

Targeting DNA Damage Response-Mediated Resistance in Non-Small Cell Lung Cancer: From Mechanistic Insights to Drug Development

open access: yesCurrent Oncology
Non-small cell lung cancer (NSCLC) remains a major contributor to cancer-related deaths worldwide, with therapeutic resistance presenting a critical clinical hurdle.
Xue Gong, Yongzhao Zhou, Yi Deng
doaj   +1 more source

The burden of disease-specific multimorbidity among older adults in India and its states: evidence from LASI

open access: yesBMC Geriatrics, 2023
Background Around the world, advances in public health and changes in clinical interventions have resulted in increased life expectancy. Multimorbidity is becoming more of an issue, particularly in countries where the population is rapidly ageing.
Priyanka Patel   +2 more
doaj   +1 more source

Research on patients with multiple health conditions: different constructs, different views, one voice [PDF]

open access: yes, 2011
Technological advances, improvements in medical care and public health policies have resulted in a growing proportion of patients with multiple health conditions.
Valderas, J.M., Mercer, S.W., Fortin, M.
core   +5 more sources

Epidemiology of multiple chronic conditions: an international perspective [PDF]

open access: yes, 2013
The epidemiology of multimorbidity, or multiple chronic conditions (MCCs), is one of the research priority areas of the U.S. Department of Health and Human Services (HHS) by its Strategic Framework on MCCs.
François G. Schellevis MD, PhD   +2 more
core   +1 more source

Socioeconomic context, individual characteristics, and multimorbidity among older adults: a nationwide cross-sectional study [PDF]

open access: yesGeriatrics, Gerontology and Aging
Objectives: The study investigated the prevalence of multimorbidity among older adults and its association with socioeconomic context and individual characteristics.
João Vitor Rodrigues   +3 more
doaj   +1 more source

Effect of multimorbidity on hypertension management

open access: yesScientific Reports, 2023
Multimorbidity, the coexistence of multiple health conditions, is associated with functional decline, disability, and mortality. We aimed to investigate the effects of multimorbidity on hypertension treatment and control rates by analyzing data from the ...
Eunjeong Ji   +4 more
doaj   +1 more source

Enhancing research quality and reporting: why the Journal of Comorbidity is now publishing study protocols [PDF]

open access: yes, 2014
The Journal of Comorbidity was launched in 2011 and has since become established as a high-quality journal that publishes open-access, peer-reviewed articles, with a focus on advancing the clinical management of patients with comorbidity/multimorbidity ...
Marjan van den Akker (41854)   +9 more
core   +1 more source

Efficacy and safety of neoadjuvant targeted therapy in non-small cell lung cancer: a systematic review and meta-analysis

open access: yesSystematic Reviews
Introduction Epidermal growth factor receptor (EGFR) mutations are major oncogenic drivers in non-small cell lung cancer (NSCLC), occurring in 30–50% of Asian patients. Neoadjuvant EGFR-tyrosine kinase inhibitors (EGFR-TKIs) may improve surgical outcomes
Honglin Li   +6 more
doaj   +1 more source

Multimorbidity's many challenges [PDF]

open access: yesBMJ, 2007
Patients with multiple conditions are the rule rather than the exception in primary care.1 In a recent study of 21 family practices in the Saguenay region, Quebec, the prevalence of multimorbidity was 69% in 18-44 year olds, 93% in 45-64 year olds, and 98% in those aged over 65, and the number of chronic conditions varied from 2.8 in the youngest to 6 ...
Fortin, Martin   +4 more
openaire   +3 more sources

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