Results 71 to 80 of about 56,158 (307)

Alzheimer’s Disease–Thrombosis Comorbidity: A Growing Body of Evidence from Patients and Animal Models

Cells
Background/Objectives: A growing body of evidence is amassing in the literature suggesting a correlation between Alzheimer’s disease (AD) and thrombotic vascular complications, which led to the suggestive hypothesis that thrombosis may contribute to AD ...
Joanna Koch-Paszkowski, Christopher Sennett, Giordano Pula   +2 more
doaj   +1 more source

Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis

Animal Research and One Health, EarlyView.
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong, Ning Liu, Weining Kong, Xiang Gao, Feifei Guan, Shan Gao, Yuanwu Ma   +6 more
wiley   +1 more source

Research on patients with multiple health conditions: different constructs, different views, one voice [PDF]

, 2011
Technological advances, improvements in medical care and public health policies have resulted in a growing proportion of patients with multiple health conditions.
Valderas, J.M., Stewart W. Mercer, Martin Fortin, Jose M. Valderas, Valderas, Jose M., Fortin, Martin, Mercer, S.W., Fortin, M., Mercer, Stewart W.   +8 more
core   +1 more source

The prevalence of multimorbidity and associations with lifestyle factors among middle-aged Canadians: an analysis of Canadian Longitudinal Study on Aging data

BMC Public Health, 2019
Background Multimorbidity can be defined as the presence of more than one chronic condition in an individual. Research on multimorbidity has predominantly focused on older adults and few studies have examined multimorbidity in middle-aged people.
Mohammad Nazmus Sakib, Shahin Shooshtari, Philip St. John, Verena Menec   +3 more
doaj   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Measuring multimorbidity in hospitalised patients using linked hospital episode data: comparison of two measures

International Journal of Population Data Science, 2019
Introduction Multimorbidity is a complex and growing health challenge. There is no accepted “gold standard” multimorbidity measure for hospital resource planning, and few studies have compared measures in hospitalised patients.
Lynn Robertson, Dolapo Ayansina, Marjorie Johnston, Angharad Marks, Corri Black   +4 more
doaj   +1 more source

Association between multimorbidity patterns and disability among older people covered by long-term care insurance in Shanghai, China

BMC Public Health, 2021
Background Functional disability and multimorbidity are common among older people. However, little is known about the relationship between functional disability and different multimorbidity combinations.
Zijing Wang, Wenjia Peng, Mengying Li, Xinghui Li, Tingting Yang, Cancan Li, Huosheng Yan, Xianjie Jia, Zhi Hu, Ying Wang   +9 more
doaj   +1 more source

Prescribing of Medication to Prevent Glucocorticoid Harms in Patients With Polymyalgia Rheumatica: A Cross‐Sectional Study and Two Emulated Target Trials in the Clinical Practice Research Datalink Aurum

Arthritis &Rheumatology, EarlyView.
Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig, David Jenkinson, James Bailey, Samantha Hider, Ian C. Scott, Sara Muller   +5 more
wiley   +1 more source

Ageing and the epidemiology of multimorbidity [PDF]

European Respiratory Journal, 2014
The world’s population is ageing and an important part of this demographic shift is the development of chronic illness. In short, a person who does not die of acute illnesses, such as infections, and survives with chronic illnesses is more likely to develop additional chronic illnesses.
Miguel J, Divo, Carlos H, Martinez, David M, Mannino   +2 more
openaire   +2 more sources

Noncommunicable disease and multimorbidity in young adults with cerebral palsy [PDF]

, 2018
Daniel G Whitney,1 Edward A Hurvitz,1 Jennifer M Ryan,2,3 Maureen J Devlin,4 Michelle S Caird,5 Zachary P French,1 Elie C Ellenberg,1 Mark D Peterson1 1Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann ...
Mark Peterson, Hurvitz EA, Caird MS, Daniel Whitney, Devlin MJ, Ellenberg, EC, Maureen Devlin, Michelle Caird, Ryan JM, Peterson MD, Whitney, DG, Ryan, JM, Caird, MS, Whitney DG, Devlin, MJ, Elie Ellenberg, Ellenberg EC, French, ZP, French ZP, Edward Hurvitz, Jennifer Ryan, Peterson, MD, Zachary French, Hurvitz, EA   +23 more
core   +1 more source