Results 91 to 100 of about 56,158 (307)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Multimorbidity in chronic disease: impact on health care resources and costs [PDF]

open access: yes, 2016
Steven M McPhail1,2 1Centre for Functioning and Health Research, Metro South Health, 2Institute of Health and Biomedical Innovation and School of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD, Australia Abstract ...
McPhail SM, McPhail, Steven M.
core   +2 more sources

The association between multiple long‐term conditions and dementia: A UK cohort study

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Studies examining the risk of dementia in people with multimorbidity are commonly conducted in research cohorts or outside the UK. Multimorbidity has historically been associated with aging, but recent research suggests that more than half ...
Hilary Shepherd   +5 more
doaj   +1 more source

Polypharmacy burden and incident epilepsy among older adults in the United States

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives To estimate the prevalence of polypharmacy among older adults with incident epilepsy and to describe the most common combinations of drug classes filled prior to epilepsy diagnosis. Polypharmacy—the concurrent use of multiple medications—is common in older adults with epilepsy, but little is known about its burden and specific ...
Galen Shearn‐Nance   +9 more
wiley   +1 more source

ABC of Multimorbidity [PDF]

open access: yes, 2014
ABC of Multimorbidity is the first title to provide primary care practitioners with a practical approach to the complex issues of treating and managing patients with more than one morbidity.<p></p> Ageing populations and earlier diagnosis ...

core  

Estimating multimorbidity prevalence with the Canadian Chronic Disease Surveillance System [PDF]

open access: yes, 2017
Introduction: The Public Health Agency of Canada’s Canadian Chronic Disease Surveillance System (CCDSS) uses a validated, standardized methodology to estimate prevalence of individual chronic diseases, such as diabetes.
Lisa M. Lix, Allison Feely, Kim Reimer
core   +1 more source

Long‐Term Trends and Projections of the Global Epilepsy Burden: Insights From the Global Burden of Disease Study 2021

open access: yesHealth Care Science, EarlyView.
Targeted interventions addressing socioeconomic inequalities and health service disparities are essential for mitigating future epilepsy burdens, especially in low‐resource settings. ABSTRACT Background Epilepsy is a common neurological disorder imposing significant global health burdens. A comprehensive understanding of its temporal and spatial trends
Du Cai   +14 more
wiley   +1 more source

Applying Change Models and Methods During a Period of Vast Digital Transformation: A Systematic Review of Practice in Healthcare

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Introduction Reflection and learning about the use of virtual care in healthcare delivery has become a central goal for health systems internationally. Insights drawn in the aftermath of the COVID‐19 pandemic have led to vast changes to embed virtual care in health care delivery. This study explored the methodologies used to manage change that
Rebecca McDonnell   +12 more
wiley   +1 more source

Extended Consultations as a Trial Intervention in General Practice: Experiences of Patients with Complex Multimorbidities

open access: yesPatient Preference and Adherence
Rosa Fryd,1– 4 Barbara Ann Barrett,1,4,5 Sanne Lykke Lundstrøm,1,6 Anne Frølich,1,5 Iben Charlotte Aamann1,4,5,7 1Innovation and Research Centre for Multimorbidity, NSR Hospital, Slagelse, Denmark; 2Section for Global Health, Department of Public Health,
Fryd R   +4 more
doaj  

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