Results 51 to 60 of about 56,158 (307)

The Multimorbidity and Lifestyle Correlates in Chinese Population Residing in Macau: Findings from a Community-Based Needs Assessment Study [PDF]

, 2023
Multimorbidity has become one of the most pressing public health concerns worldwide. The objectives of this study were to understand the prevalence of multimorbidity and its relationship with lifestyle factors among Chinese adults in Macau, and to ...
Qingling Yang, Shao Ling WANG, Oi Ching Bernice Lam Nogueira, Yang Gao, Molasiotis, A., Fei Wan Ngai, Harry Haoxiang Wang, Yaojie Xie, Yang (Gemma) Gao, Chun Hao, Alex Molasiotis, Ming Liu, Alice Loke, Shaoling Wang, Quanzhi Zhang, Xie, Yao Jie, Harry H.X. Wang, Dexing Zhang, Alice Yuen Loke   +18 more
core   +1 more source

Sex-specific patterns and lifetime risk of multimorbidity in the general population: a 23-year prospective cohort study

BMC Medicine, 2022
Background Multimorbidity poses a major challenge for care coordination. However, data on what non-communicable diseases lead to multimorbidity, and whether the lifetime risk differs between men and women are lacking.
Premysl Velek, Annemarie I. Luik, Guy G. O. Brusselle, Bruno Ch. Stricker, Patrick J. E. Bindels, Maryam Kavousi, Brenda C. T. Kieboom, Trudy Voortman, Rikje Ruiter, M. Arfan Ikram, M. Kamran Ikram, Evelien I. T. de Schepper, Silvan Licher   +12 more
doaj   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

Arthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group   +7 more
wiley   +1 more source

Epidemiology of multiple chronic conditions: an international perspective [PDF]

, 2013
The epidemiology of multimorbidity, or multiple chronic conditions (MCCs), is one of the research priority areas of the U.S. Department of Health and Human Services (HHS) by its Strategic Framework on MCCs.
François G. Schellevis MD, PhD, Schellevis, François G., Schellevis, F.G.   +2 more
core   +2 more sources

Determinants of the onset and development of multimorbidity in different subpopulations of older Chinese adults: insights from the China Health and Retirement Longitudinal Study

Annals of Medicine
Background and objectives Multimorbidity trajectories help to analyze the onset and development of multimorbidity over time and are an important public health matter.
Changcong Wang, Shutong Wang, Haitao Yu, Xinyue Zhang, Meng Zhang, Dongmei Mu   +5 more
doaj   +1 more source

The burden of disease-specific multimorbidity among older adults in India and its states: evidence from LASI

BMC Geriatrics, 2023
Background Around the world, advances in public health and changes in clinical interventions have resulted in increased life expectancy. Multimorbidity is becoming more of an issue, particularly in countries where the population is rapidly ageing.
Priyanka Patel, T. Muhammad, Harihar Sahoo   +2 more
doaj   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Disparities in multiple chronic conditions within populations [PDF]

, 2013
Disadvantaged populations are disproportionately affected by multiple chronic conditions (MCCs), yet few studies examine the prevalence, outcomes, or effectiveness of MCC interventions in minority and socioeconomically deprived individuals and ...
Efrat Shadmi RN, PhD, Shadmi, Efrat
core   +2 more sources

Management of tunneled-cuffed catheters in hemodialysis patients with hypotension and recurrent central venous thrombosis: A single-center retrospective cohort study

Science Progress
Objective To evaluate management strategies of tunneled-cuffed catheters (TCCs) in hemodialysis (HD) patients with hypotension and recurrent central venous thrombosis.
Jibo Sun, Hong Fan, Tianlei Cui
doaj   +1 more source

Targeting DNA Damage Response-Mediated Resistance in Non-Small Cell Lung Cancer: From Mechanistic Insights to Drug Development

Current Oncology
Non-small cell lung cancer (NSCLC) remains a major contributor to cancer-related deaths worldwide, with therapeutic resistance presenting a critical clinical hurdle.
Xue Gong, Yongzhao Zhou, Yi Deng
doaj   +1 more source