Gastric cancer with radiographically occult metastatic disease: Biology, challenges, and diagnostic approaches [PDF]
Gastric adenocarcinoma is an aggressive cancer that demonstrates heterogeneous biology depending on patient ethnicity, tumor location, tumor type, and genetic profile.
Fangman, Benjamin +3 more
core +2 more sources
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Caregiver Burden and Perceived Health Competence when Caring for Family Members Diagnosed with Alzheimer’s Disease and Related Dementia [PDF]
Purpose: To identify if there is a relationship between perceived health competence and burden of care of informal caregivers of family members with Alzheimer’s Disease and Related Dementia (ADRD).
Bailes, Christine
core
Cost‐effectiveness of asthma clinic approach in the management of chronic asthma in Australia
Objectives: To compare cost‐effectiveness of an asthma clinic that would provide education, promotion of self‐monitoring of symptoms, regular review of treatment by a medical practitioner and a written asthma action plan to current practice in Australia.
Vittal Mogasale, Theo Vos
doaj +1 more source
Humanistic Burden of Huntington Disease
Huntington disease (HD) is a rare, inherited, and highly complex neurodegenerative disorder with no currently approved disease-modifying treatments. We investigated the effect of HD on health-related quality of life and other patient-reported outcomes in the Huntington's Disease Burden of Illness (HDBOI) study.The HDBOI study is a retrospective, cross ...
Rodriguez Santana, Idaira +12 more
openaire +2 more sources
Interactive effects of vascular risk burden and advanced age on cerebral blood flow. [PDF]
Vascular risk factors and cerebral blood flow (CBF) reduction have been linked to increased risk of cognitive impairment and Alzheimer's disease (AD); however the possible moderating effects of age and vascular risk burden on CBF in late life remain ...
Bangen, Katherine J +10 more
core +1 more source
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker +7 more
wiley +1 more source
Health, Environment and the Burden of Disease: A Guidance Note [PDF]
This guidance note examines the conditions which determine whether an environmental hazard is responsible for a substantial amount of disease and whether feasible measures are available to prevent it.
core
Селянське і шляхетне, селянське і міське: взаємозв’язок народної та елітарної культури в середземноморській баладі про шляхетну пастушку [PDF]
The plot of the Mediterranean ballad in the Romance tradition, known under the title of Noble pastora (the Noble Shepherdess), is analysed in this paper, largely on the examples of Castillian and Dalmatian variants.
Aicher +11 more
core +1 more source

