Results 61 to 70 of about 80,215 (303)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Origin and Attribution of the Items in Eastern European Champlevé Enamels Style (Late 2nd – 4th Centuries) Found South-Eastward of the Main Dnieper Area

open access: yesНижневолжский археологический вестник
This article examines the origin and attribution of ornaments in Eastern European style found to the south and east of the main Dnieper area of such artifacts. Previously unknown artifacts are introduced into scientific circulation.
Oleg A. Radyush
doaj   +1 more source

Archaeological Evidence of Proto-Bulgarian Presence in the Territory of Southern Bulgaria

open access: yesПоволжская археология, 2012
The findings from Southern Bulgaria, mainly dated back to the 8th century, which researchers associate with proto-Bulgarian presence in the territory south of Stara Planina, are discussed. These are primarily funerary complexes of the 1st half through to
Borisov Boris
doaj   +1 more source

The Stover Lake Site (41BW8) on the lower Sulphur River, Bowie County, Texas [PDF]

open access: yes, 2015
The Stover Lake site (41BW8) is an ancestral Caddo cemetery and habitation site on a natural alluvial rise in the Sulphur River floodplain, about 1.6 km east of the Lake Wright Patman dam.
Perttula, Timothy K.
core   +1 more source

Diet uniformity at an early farming community in northwest Anatolia (Turkey) : carbon and nitrogen isotope studies of bone collagen at Aktopraklik [PDF]

open access: yes, 2017
Aktopraklık is a settlement site composed of three areas (A–C) in the Marmara region of northwest Anatolia, with phases of occupation that date to the Late Neolithic and Early Chalcolithic periods, mid-seventh to mid-sixth millennium bc (ca.
Alpaslan-Roodenberg, Songül   +5 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

The Kashi Artefacts in the Burials of the Zmeisky Catacomb Cemetery

open access: yesПоволжская археология, 2018
The paper aims to the chronology of burials within the chambers and in the undercats of the catacombs and pit interments of the Zmeisky catacomb burial ground in Republic of North Ossetia-Alania (excavations 2013–2014), based on the analysis of kashi ...
Leontyeva Anna S.
doaj   +1 more source

A Quantitative Study of the Linear Pottery Culture Cemetery “Aiterhofen-Ödmühle”

open access: yesOpen Archaeology, 2021
This article emphasises on the results of the master´s thesis “Burials in Bytes. A Quantitative Study of Linear Pottery Cemeteries in Austria, Bohemia, Moravia and Southern Germany” and further elaborates on interpretations of identified patterns at ...
Hahnekamp Yanik
doaj   +1 more source

Comments on Caddo Origins in Northwest Louisiana [PDF]

open access: yes, 2009
This paper presents some of my thoughts on the issue of Caddo origins from the perspective of the Red River drainage in northwest Louisiana. These ideas were assembled prior to the Caddo discussion group meeting held in December 2008 and have been only ...
Girard, Jeffery S.
core   +1 more source

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