Results 81 to 90 of about 81,142 (309)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The Norman Site: Descriptions [PDF]
, 2000 The Norman site (34WG2) lay on a terrace on the west side of the Neosho (Grand) River in Wagoner County, Oklahoma. Throughout much of its course within Oklahoma, this river flows along the western boundary of the Ozark Uplift.
Albert, Lois E.
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The three burials of Melquiades DGP
, 2008 In this talk I review three fatal flaws of the DGP braneworld model, which has been put forward as a possible model for late time acceleration without a cosmological constant: Ghosts, Cosmological Crashes, and Instability of the 5D vacuum.
Gregory, Ruth
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The ‘invisible’ pits: how informative are old excavations in discussing Middle Palaeolithic burials?
Materiale și Cercetări Arheologice, 2016 In this paper I focus on the potential of Palaeolithic sites excavated before the establishment of modern methods, aiming to provide reliable information on current debates. Specifically, I will address the reliability of the information coming from such
Doboș, A.
doaj +1 more source
Human Skeletal Remains from the Tyson Site (41SY92) [PDF]
, 1994 During the 1993 field season at the Tyson site (41SY92), conducted by the East Texas and Northeast Texas Archaeological societies, two burial features were uncovered.
Dockall, Helen D.
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FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
The Keasler site (41HS235), a Titus Phase Cemetery in the Little Cypress Creek Basin, Harrison County, Texas [PDF]
, 2015 The Keasler site (41HS235) is a Late Caddo period, Titus phase (ca. A.D. 1430-1680) cemetery in the East Texas Pineywoods. The site was excavated by collectors in the late 1970s, including Red McFarland, one of the more active looters of Caddo burials in
Perttula, Timothy K.
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source