Results 101 to 110 of about 29,723 (221)
Characterization of the Burkholderia cenocepacia TonB Mutant as a Potential Live Attenuated Vaccine
Burkholderia cenocepacia is an opportunistic pathogen prevalent in cystic fibrosis patients, which is particularly difficult to treat, causing chronic and eventually fatal infections.
Gonzalo A. Pradenas +2 more
doaj +1 more source
Putrescine Reduces Antibiotic-Induced Oxidative Stress as a Mechanism of Modulation of Antibiotic Resistance in Burkholderia cenocepacia [PDF]
Communication of antibiotic resistance among bacteria via small molecules is implicated in transient reduction of bacterial susceptibility to antibiotics, which could lead to therapeutic failures aggravating the problem of antibiotic resistance. Released
El-Halfawy, Omar M., Valvano, Miguel A.
core +1 more source
Burkholderia cenocepacia infections are difficult to treat and there is an urgent need for alternative (combination) treatments. The use of anti-virulence therapies in combination with antibiotics is a possible strategy to increase the antimicrobial ...
Mona Bové, T. Coenye
semanticscholar +1 more source
Characterization of a bifunctional catalaseâperoxidase ofBurkholderia cenocepacia [PDF]
Isolates of Burkholderia cenocepacia express a putative haem-binding protein (molecular mass 97 kDa) that displays intrinsic peroxidase activity. Its role has been re-evaluated, and we now show that it is a bifunctional catalase-peroxidase, with activity against tetramethylbenzidine (TMB), o-dianisidine, pyrogallol, and 2,2'-azino-bis(3 ...
Charalabous, Panagoula +5 more
openaire +3 more sources
Why genes evolve faster on secondary chromosomes in bacteria [PDF]
In bacterial genomes composed of more than one chromosome, one replicon is typically larger, harbors more essential genes than the others, and is considered primary.
Cooper, Vaughn S. +3 more
core +1 more source
Abstract Diffusible signal factor (DSF)‐family quorum sensing (QS) signals are widely utilized by many pathogenic bacteria to modulate various biological functions and virulence. Previous studies showed that cis‐2‐decenoic acid (cis‐DA) is involved in the modulation of biofilm dispersion in Pseudomonas aeruginosa, but the regulatory mechanism is ...
Shihao Song +15 more
wiley +1 more source
Activation Of The Pyrin Inflammasome By Intracellular Burkholderia Cenocepacia [PDF]
Abstract Burkholderia cenocepacia is an opportunistic pathogen that causes chronic infection and induces progressive respiratory inflammation in cystic fibrosis patients. Recognition of bacteria by mononuclear cells generally results in the activation of caspase-1 and processing of IL-1β, a major proinflammatory cytokine.
Mikhail A, Gavrilin +10 more
openaire +3 more sources
Targeting the nonmevalonate pathway in Burkholderia cenocepacia increases susceptibility to certain β-lactam antibiotics [PDF]
The nonmevalonate pathway is the sole pathway for isoprenoid biosynthesis in Burkholderia cenocepacia and is possibly a novel target for the development of antibacterial chemotherapy.
Coenye, Tom +4 more
core +2 more sources
ABSTRACT Background Dry skin is a prevalent dermatological concern influenced by environmental factors and characterized by compromised skin barrier integrity. In addition to this, skin microbiota is involved and plays a crucial role in maintaining microbial flora balance.
Camilla D'Antonio +6 more
wiley +1 more source
Diffusible Signal Factor (DSF)-dependent quorum sensing in pathogenic bacteria and its exploitation for disease control [PDF]
Cell-to-cell signals of the Diffusible Signal Factor (DSF) family are cis-2-unsaturated fatty acids of differing chain length and branching pattern. DSF signalling has been described in diverse bacteria to include plant and human pathogens where it acts ...
Dow, J. Maxwell
core +1 more source

