Results 101 to 110 of about 29,723 (221)

Characterization of the Burkholderia cenocepacia TonB Mutant as a Potential Live Attenuated Vaccine

open access: yesVaccines, 2017
Burkholderia cenocepacia is an opportunistic pathogen prevalent in cystic fibrosis patients, which is particularly difficult to treat, causing chronic and eventually fatal infections.
Gonzalo A. Pradenas   +2 more
doaj   +1 more source

Putrescine Reduces Antibiotic-Induced Oxidative Stress as a Mechanism of Modulation of Antibiotic Resistance in Burkholderia cenocepacia [PDF]

open access: yes, 2014
Communication of antibiotic resistance among bacteria via small molecules is implicated in transient reduction of bacterial susceptibility to antibiotics, which could lead to therapeutic failures aggravating the problem of antibiotic resistance. Released
El-Halfawy, Omar M., Valvano, Miguel A.
core   +1 more source

The anti-virulence activity of the non-mevalonate pathway inhibitor FR900098 towards Burkholderia cenocepacia is maintained during experimental evolution.

open access: yesMicrobiology, 2022
Burkholderia cenocepacia infections are difficult to treat and there is an urgent need for alternative (combination) treatments. The use of anti-virulence therapies in combination with antibiotics is a possible strategy to increase the antimicrobial ...
Mona Bové, T. Coenye
semanticscholar   +1 more source

Characterization of a bifunctional catalase–peroxidase ofBurkholderia cenocepacia [PDF]

open access: yesFEMS Immunology & Medical Microbiology, 2007
Isolates of Burkholderia cenocepacia express a putative haem-binding protein (molecular mass 97 kDa) that displays intrinsic peroxidase activity. Its role has been re-evaluated, and we now show that it is a bifunctional catalase-peroxidase, with activity against tetramethylbenzidine (TMB), o-dianisidine, pyrogallol, and 2,2'-azino-bis(3 ...
Charalabous, Panagoula   +5 more
openaire   +3 more sources

Why genes evolve faster on secondary chromosomes in bacteria [PDF]

open access: yes, 2010
In bacterial genomes composed of more than one chromosome, one replicon is typically larger, harbors more essential genes than the others, and is considered primary.
Cooper, Vaughn S.   +3 more
core   +1 more source

Cis‐2‐decenoic acid modulates Pseudomonas aeruginosa virulence through a noncanonical transcriptional regulator

open access: yesmLife, Volume 4, Issue 6, Page 623-637, December 2025.
Abstract Diffusible signal factor (DSF)‐family quorum sensing (QS) signals are widely utilized by many pathogenic bacteria to modulate various biological functions and virulence. Previous studies showed that cis‐2‐decenoic acid (cis‐DA) is involved in the modulation of biofilm dispersion in Pseudomonas aeruginosa, but the regulatory mechanism is ...
Shihao Song   +15 more
wiley   +1 more source

Activation Of The Pyrin Inflammasome By Intracellular Burkholderia Cenocepacia [PDF]

open access: yesA35. RECENT ADVANCES IN PHAGOCYTE BIOLOGY, 2012
Abstract Burkholderia cenocepacia is an opportunistic pathogen that causes chronic infection and induces progressive respiratory inflammation in cystic fibrosis patients. Recognition of bacteria by mononuclear cells generally results in the activation of caspase-1 and processing of IL-1β, a major proinflammatory cytokine.
Mikhail A, Gavrilin   +10 more
openaire   +3 more sources

Targeting the nonmevalonate pathway in Burkholderia cenocepacia increases susceptibility to certain β-lactam antibiotics [PDF]

open access: yes, 2018
The nonmevalonate pathway is the sole pathway for isoprenoid biosynthesis in Burkholderia cenocepacia and is possibly a novel target for the development of antibacterial chemotherapy.
Coenye, Tom   +4 more
core   +2 more sources

Exploring Microbial and Biophysical Aspects of Dry Skin: In Vivo Test of a Novel Skincare Formulation

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 12, December 2025.
ABSTRACT Background Dry skin is a prevalent dermatological concern influenced by environmental factors and characterized by compromised skin barrier integrity. In addition to this, skin microbiota is involved and plays a crucial role in maintaining microbial flora balance.
Camilla D'Antonio   +6 more
wiley   +1 more source

Diffusible Signal Factor (DSF)-dependent quorum sensing in pathogenic bacteria and its exploitation for disease control [PDF]

open access: yes, 2016
Cell-to-cell signals of the Diffusible Signal Factor (DSF) family are cis-2-unsaturated fatty acids of differing chain length and branching pattern. DSF signalling has been described in diverse bacteria to include plant and human pathogens where it acts ...
Dow, J. Maxwell
core   +1 more source

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