Results 71 to 80 of about 29,723 (221)

Identification of New L-Fucosyl and L-Galactosyl Amides as Glycomimetic Ligands of TNF Lectin Domain of BC2L-C from Burkholderia cenocepacia

Molecules, 2023
The inhibition of carbohydrate-lectin interactions is being explored as an efficient approach to anti adhesion therapy and biofilm destabilization, two alternative antimicrobial strategies that are being explored against resistant pathogens.
Sarah Mazzotta, Giulia Antonini, F. Vasile, É. Gillon, Jon Lundstrøm, A. Varrot, L. Belvisi, A. Bernardi   +7 more
semanticscholar   +1 more source

Invasion and biofilm formation of Burkholderia dolosa is comparable with Burkholderia cenocepacia and Burkholderia multivorans [PDF]

Journal of Cystic Fibrosis, 2007
Colonisation with Burkholderia cepacia complex pathogens has been associated with accelerated decline in cystic fibrosis (CF) patients. The two most common species among the CF community are Burkholderia cenocepacia and Burkholderia multivorans. However, Burkholderia dolosa has recently been causing concern due to its transmissibility and virulence in ...
Caraher, Emma, Duff, Caroline, Mullen, Tracy, Mc Keon, Suzanne, Murphy, Philip, Callaghan, Máire, McClean, Siobhán   +6 more
openaire   +3 more sources

Characterization of the Burkholderia cenocepacia J2315 Surface-Exposed Immunoproteome [PDF]

Vaccines, 2020
Infections by the Burkholderia cepacia complex (Bcc) remain seriously life threatening to cystic fibrosis (CF) patients, and no effective eradication is available. A vaccine to protect patients against Bcc infections is a highly attractive therapeutic option, but none is available.
Sílvia A. Sousa, António M.M. Seixas, Manoj Mandal, Manuel J. Rodríguez-Ortega, Jorge H. Leitão   +4 more
openaire   +5 more sources

A unique regulator contributes to quorum sensing and virulence in Burkholderia cenocepacia. [PDF]

PLoS ONE, 2012
Burkholderia cenocepacia causes chronic and life-threatening respiratory infections in immunocompromized people. The B. cenocepacia N-acyl-homoserine lactone (AHL)-dependent quorum sensing system relies on the production of AHLs by the synthases CepI and
Eoin P O'Grady, Duber F Viteri, Pamela A Sokol   +2 more
doaj   +1 more source

Prosthetic Joint Infection due to Burkholderia cenocepacia: An Opportunistic Pathogen Microbiology Section with an Expanding Spectrum of Disease [PDF]

Journal of Clinical and Diagnostic Research, 2017
Burkholderia cenocepacia is an opportunistic pathogen widespread in moist environments. It has been associated with lung infections, blood, skin and genitourinary tract infections.
Sujeesh Sebastian, Rajesh Malhotra, Rojaleen Das, Arti Kapil, Benu Dhawan   +4 more
doaj   +1 more source

Bayesian modeling of recombination events in bacterial populations [PDF]

, 2008
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fairly closely related species.
A Baldwin, A Baldwin, A Baldwin, A Rambaut, A Skalka, Adam Baldwin, C Fraser, Chris Dowson, CP Robert, CX Chan, D Falush, D Husmeier, D Posada, DJ Hand, E Mahenthiralingam, E Mahenthiralingam, EHL Aarts, Eshwar Mahenthiralingam, FM Cohan, J Corander, J Corander, J Corander, J Corander, J Felsenstein, J Hein, J Maynard Smith, JG Lawrence, JS Sinsheimer, Jukka Corander, JV Braun, M Arenas, M Hasegawa, MA Suchard, MJ Schervish, NC Grassly, P Marttinen, Pekka Marttinen, R Jain, RA Elton, S Sawyer, SA Sisson, VN Minin, VN Minin, William P Hanage, WJ Wiersinga, WP Hanage, X Didelot   +46 more
core   +5 more sources

Functional Analysis of the Burkholderia cenocepacia ZmpA Metalloprotease [PDF]

Journal of Bacteriology, 2005
ABSTRACT Burkholderia cenocepacia ZmpA is expressed as a preproenzyme typical of thermolysin-like proteases such as Pseudomonas aeruginosa LasB and Bacillus thermoproteolyticus thermolysin. The zmpA gene was expressed using the pPRO-EXHTa His
C, Kooi, C R, Corbett, P A, Sokol
openaire   +2 more sources

Effect of β-lactamase inhibitors on in vitro activity of β-lactam antibiotics against Burkholderia cepacia complex species [PDF]

, 2016
Background: Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients. Intrinsic resistance to a wide range of antimicrobial agents, including a variety of beta-
Coenye, Tom, Everaert, Annelien
core   +2 more sources

Genome Wide Identification, Characterization and Evolutionary Analysis of T6SS in Burkholderia cenocepacia Strains [PDF]

International Journal Bioautomation
Pathogens of the Burkholderia genus are causing diseases in a diverse variety of hosts. After the discovery of T6SS, it was found to play a pivotal role in virulence and other pathogenicity factors in different pathogenic Burkholderia species.
Sardarni K. Raza, Muhammad Ibrahim, Kainaat, Afshan Farid, Sardar S. N. Khan, Aqsa Talat, Tayyaba Arzoo, Syeda I. Fatima, Abdul Waheed   +8 more
doaj   +1 more source

Environmental Burkholderia cenocepacia Strain Enhances Fitness by Serial Passages during Long-Term Chronic Airways Infection in Mice [PDF]

, 2017
Burkholderia cenocepacia is an important opportunistic pathogen in cystic fibrosis (CF) patients, and has also been isolated from natural environments. In previous work, we explored the virulence and pathogenic potential of environmental B.
Ascenzioni, Fiorentina, Bevivino, Annamaria, Bragonzi, Alessandra, Coladarci, Ivan, Paroni, Moira, Pirone, Luisa   +5 more
core   +3 more sources