Activation Of The Pyrin Inflammasome By Intracellular Burkholderia Cenocepacia [PDF]
Abstract Burkholderia cenocepacia is an opportunistic pathogen that causes chronic infection and induces progressive respiratory inflammation in cystic fibrosis patients. Recognition of bacteria by mononuclear cells generally results in the activation of caspase-1 and processing of IL-1β, a major proinflammatory cytokine.
Mikhail A, Gavrilin +10 more
openaire +3 more sources
The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349 [PDF]
In Burkholderia cenocepacia, the second messenger cyclic diguanosine monophosphate (c-di-GMP) has previously been shown to positively regulate biofilm formation and the expression of cellulose and type-I fimbriae genes through binding to the ...
Ryan, Robert P +4 more
core +1 more source
Burkholderia cenocepacia Keratitis With Exogenous Endopthalmitis: A Complex Combination. [PDF]
In this report, we present a case of Burkholderia cenocepacia (B. cenocepacia)keratitis with exogenous endophthalmitis in a post-vitrectomy eye. The patient was a 68-year-old man with a history of treated corneal laceration and endophthalmitis who presented with acute pain, redness, and lid swelling affecting the left eye following working at a palm ...
Bahaman Shah NS +3 more
europepmc +3 more sources
Respiratory tract infections by the opportunistic pathogen Burkholderia cenocepacia often lead to severe lung damage in cystic fibrosis (CF) patients.
Ian Vandenbussche +5 more
doaj +3 more sources
Development of vaccines against burkholderia pseudomallei. [PDF]
Burkholderia pseudomallei is a Gram-negative bacterium which is the causative agent of melioidosis, a disease which carries a high mortality and morbidity rate in endemic areas of South East Asia and Northern Australia.
Patel, Natasha +23 more
core +1 more source
Molecular Mechanisms of Chlorhexidine Tolerance in Burkholderia cenocepacia Biofilms [PDF]
ABSTRACT The high tolerance of biofilm-grown Burkholderia cepacia complex bacteria against antimicrobial agents presents considerable problems for the treatment of infected cystic fibrosis patients and the implementation of infection control guidelines.
Coenye T +6 more
openaire +3 more sources
Multilocus sequence typing scheme that provides both species and strain differentiation for the Burkholderia cepacia complex [PDF]
A single multilocus sequence typing (MLST) scheme was developed for precise characterization of the opportunistic pathogens of Burkholderia cepacia complex (BCC), a group composed of at least nine closely related species.
J. R. Govan +34 more
core +1 more source
Multilocus sequence typing breathes life into a microbial metagenome [PDF]
Shot-gun sequencing of DNA isolated from the environment and the assembly of metagenomes from the resulting data has considerably advanced the study of microbial diversity.
Vandamme Peter +23 more
core +1 more source
Complete Genome Sequence of Burkholderia cenocepacia Phage Magia
Burkholderia cenocepacia is a Gram-negative bacterium that is implicated in respiratory infections. The 44,942-bp genome of Magia, a phage infecting B. cenocepacia , does not appear to have strong overall similarity to other known phages.
David Gafford-Gaby +6 more
openaire +2 more sources
A unique regulator contributes to quorum sensing and virulence in Burkholderia cenocepacia. [PDF]
Burkholderia cenocepacia causes chronic and life-threatening respiratory infections in immunocompromized people. The B. cenocepacia N-acyl-homoserine lactone (AHL)-dependent quorum sensing system relies on the production of AHLs by the synthases CepI and
Eoin P O'Grady +2 more
doaj +1 more source

