Results 71 to 80 of about 4,698 (167)

Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT Biofilms formed by mycobacteria, particularly Mycobacterium tuberculosis (Mtb), represent a major challenge in tuberculosis (TB) treatment due to their highly organized structure and their capacity to induce phenotypic drug tolerance. These three‐dimensional bacterial aggregates are embedded in a self‐produced extracellular matrix that ...
Lourdes Serrano Garcia, Cesar Augusto Roque‐Borda, Fernando Rogério Pavan, Marlus Chorilli   +3 more
wiley   +1 more source

Extracellular Particles Derived From Mesenchymal Stromal Cells Reduce Pseudomonas aeruginosa Lung Infection and Inflammation in Mice

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT The World Health Organization and the U.S. Centre for Disease Control and Prevention have reported that antibiotic‐resistant infections with Pseudomonas aeruginosa present a significant health risk worldwide. In the genetic disease Cystic Fibrosis (CF), chronic antibiotic‐resistant Pseudomonas lung infections and persistent inflammation remain
Sharanya Sarkar, Roxanna Barnaby, Zachary Faber, Lily Taub, Carolyn Roche, Lily A. Charpentier, Thomas H. Hampton, Brad Vietje, Douglas J. Taatjes, Byoung‐Kyu Cho, Young Ah Goo, Matthew J. Wargo, Daniel J. Weiss, Tracey L. Bonfield, Thomas J. Kelley, Bruce A. Stanton   +15 more
wiley   +1 more source

The Factors Involved in Plant–Insect–Microbe Interactions Expanded: Genome Analysis and Description of Frigoribacterium adelgis sp. nov.

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Aerobic Actinobacteria belonging to the genus Frigoribacterium were isolated from adelgid Adelges (Aphrastasia) pectinatae collected from a Korean fir tree. Genomic analysis showed that these bacteria encode a range of factors that may be involved in the interactions between Frigoribacterium strains, adelgids and/or Korean fir trees.
Gustė Tamošiūnaitė, Jekaterina Havelka, Raimonda Baranauskienė, Justas Lazutka, Nomeda Kuisiene   +4 more
wiley   +1 more source

Macrophages as drivers of an opportunistic infection

Microbial Cell, 2017
Opportunistic pathogens are a worldwide cause of mortality and morbidity, and infections with intrinsically antibiotic-resistant pathogens have a large clinical, social and economic impact.
Annette C. Vergunst, Nazareth Lopez Carranza, Lili Zhang, Margarida C. Gomes, Yara Tasrini, Annemarie H. Meijer, David O’Callaghan   +6 more
doaj   +1 more source

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

The FEBS Journal, Volume 293, Issue 4, Page 1168-1190, February 2026.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher, Pavel Dobeš, Jan Komárek, Lukáš Faltinek, Marek Korsák, Petra Sýkorová, Josef Houser, Michaela Wimmerová   +7 more
wiley   +1 more source

Simple and effective remediation strategies of Martian perchlorates

Soil Science Society of America Journal, Volume 90, Issue 1, January/February 2026.
Abstract Martian surface minerals have abundant perchlorate salts existing in both solid and liquid phases that will impair agricultural operations, biological life‐support systems, and in situ resource utilization due to their toxicity. Thus, simple and effective perchlorate remediation strategies will be necessary for the successful use of Martian ...
Harrison R. Coker, Aenghus C. Denvir, Julie A. Howe   +2 more
wiley   +1 more source

The mechanism of action of auranofin analogs in B. cenocepacia revealed by chemogenomic profiling

Microbiology Spectrum
Drug repurposing efforts led to the discovery of bactericidal activity in auranofin, a gold-containing drug used to treat rheumatoid arthritis. Auranofin kills Gram-positive bacteria by inhibiting thioredoxin reductase, an enzyme that scavenges reactive ...
Dustin T. Maydaniuk, Brielle Martens, Sarah Iqbal, Andrew M. Hogan, Neil Lorente Cobo, Anna Motnenko, Dang Truong, Sajani H. Liyanage, Mingdi Yan, Gerd Prehna, Silvia T. Cardona   +10 more
doaj   +1 more source

The Effect of 2-Thiocyanatopyridine Derivative 11026103 on Burkholderia Cenocepacia: Resistance Mechanisms and Systemic Impact

Antibiotics, 2019
Bacteria of the Burkholderia cepacia complex (Bcc) are associated with significant decline of lung functions in cystic fibrosis patients. Bcc infections are virtually impossible to eradicate due to their irresponsiveness to antibiotics.
Jaroslav Nunvar, Andrew M. Hogan, Silvia Buroni, Svetlana Savina, Vadim Makarov, Silvia T. Cardona, Pavel Drevinek   +6 more
doaj   +1 more source

Effects of Purple Nonsulfur Bacteria Capable of Solubilizing Potassium From Muscovite (Rhodoplanes pokkaliisoli M‐Wa‐19, Rhodocista pekingensis M‐Wa‐24 and M‐Wa‐26) on Soil Property, Potassium Uptake, Growth, and Yield of Hybrid Maize Under Greenhouse Conditions

Applied and Environmental Soil Science, Volume 2026, Issue 1, 2026.
This study was conducted to evaluate the effects of liquid purple nonsulfur bacteria capable of solubilizing potassium from muscovite (MS‐PNSB) on soil properties, potassium uptake, growth, and yield of hybrid maize under greenhouse conditions. A two‐factor experiment was arranged in a completely randomized block design with 25 treatment combinations ...
Nguyen Quoc Khuong, Nguyen Thi Viet Hoa, Tran Trong Khoi Nguyen, Le Thi My Thu, Nguyen Duc Trong, Nguyen Thanh Toan, La Cao Thang, Le Thanh Quang, Kalyani Sen   +8 more
wiley   +1 more source

Polyphasic characterisation of Burkholderia cepaciacomplex species isolated from children with cystic fibrosis

Memorias do Instituto Oswaldo Cruz, 2016
Cystic fibrosis (CF) patients with Burkholderia cepacia complex (Bcc) pulmonary infections have high morbidity and mortality. The aim of this study was to compare different methods for identification of Bcc species isolated from paediatric CF patients ...
Fernando José Vicenzi, Marcelo Pillonetto, Helena Aguilar Peres Homem de Mello de Souza, Jussara Kasuko Palmeiro, Carlos Antônio Riedi, Nelson Augusto Rosario-Filho, Libera Maria Dalla-Costa   +6 more
doaj   +1 more source