Results 41 to 50 of about 6,089 (200)

Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction [PDF]

, 2011
BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection.
Panda, G., Gurudutta Panda, Fang, K., Wang, J., Sun, Changyue, Lam, Carolyn M. C., Godinho, M., Carolyn MC Lam, Changyue Sun, Vítor AP Martins dos Santos, Lam, Carolyn M C, Chang, Suhua, Panda, Gurudutta, Lam, M.C., Kunlin Zhang, Miguel Godinho, Martins dos Santos, Vítor A P, Carolyn M C Lam, Vítor A P Martins dos Santos, Zhao, Hansheng, dos Santos, Vitor A. P. Martins, Suhua Chang, Godinho, Miguel, Hansheng Zhao, Jing Wang, Wang, Jing, Martins Dos Santos, V.A.P., Chang, S., Zhang, Kunlin, Zhang, K., Fang, Kechi, Kechi Fang, Zhao, H.   +32 more
core   +2 more sources

Human Cryptic Host Defence Peptide GVF27 Exhibits Anti-Infective Properties against Biofilm Forming Members of the Burkholderia cepacia Complex

Pharmaceuticals, 2022
Therapeutic solutions to counter Burkholderia cepacia complex (Bcc) bacteria are challenging due to their intrinsically high level of antibiotic resistance.
Andrea Bosso, Rosa Gaglione, Rocco Di Girolamo, Edwin J. A. Veldhuizen, Pilar García-Vello, Salvatore Fusco, Valeria Cafaro, Maria Monticelli, Rosanna Culurciello, Eugenio Notomista, Angela Arciello, Elio Pizzo   +11 more
doaj   +1 more source

Burkholderia cenocepacia and Burkholderia multivorans: influence on survival in cystic fibrosis [PDF]

Thorax, 2004
Burkholderia cepacia infection has been associated with a poor prognosis for patients with cystic fibrosis (CF). It is now recognised that organisms classified as B cepacia comprise a number of distinct genomic species each known as a genomovar of the B cepacia complex (BCC).
A M, Jones, M E, Dodd, J R W, Govan, V, Barcus, C J, Doherty, J, Morris, A K, Webb   +6 more
openaire   +2 more sources

New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates

Antibiotics, 2021
Bacteria of the genus Burkholderia include pathogenic Burkholderia mallei, Burkholderia pseudomallei and the Burkholderia cepacia complex (Bcc). These Gram-negative pathogens have intrinsic drug resistance, which makes treatment of infections difficult ...
Dustin Maydaniuk, Bin Wu, Dang Truong, Sajani H. Liyanage, Andrew M. Hogan, Zhong Ling Yap, Mingdi Yan, Silvia T. Cardona   +7 more
doaj   +1 more source

Burkholderia cenocepacia utilizes ferritin as an iron source [PDF]

Journal of Medical Microbiology, 2006
Burkholderia cenocepaciais a member of theBurkholderia cepaciacomplex, a group of genetically similar species that inhabit a number of environmental niches, including the lungs of patients with cystic fibrosis (CF). To colonize the lung, this bacterium requires a source of iron to satisfy its nutritional requirements for this important metal.
Paul W, Whitby, Timothy M, VanWagoner, Jennifer M, Springer, Daniel J, Morton, Thomas W, Seale, Terrence L, Stull   +5 more
openaire   +2 more sources

Burkholderia cenocepaciaInduces Macropinocytosis to Enter Macrophages [PDF]

BioMed Research International, 2018
Burkholderia cenocepaciais an opportunistic pathogen that infects individuals with cystic fibrosis, chronic granulomatous disease, and other immunocompromised states.B. cenocepaciasurvives in macrophages in membrane-bound vacuoles; however, the mechanism by whichB. cenocepaciagains entry into macrophages remains unknown.
Roberto Rosales-Reyes, Concepción Sánchez-Gómez, Vianney Ortiz-Navarrete, José Ignacio Santos-Preciado   +3 more
openaire   +2 more sources

Complete Genome Sequence of Burkholderia cenocepacia Phage Mica

Microbiology Resource Announcements, 2021
Burkholderia cenocepacia is a multidrug-resistant Gram-negative pathogen known to colonize patients with chronic granulomatous disease and cystic fibrosis. Here, we describe Burkholderia phage Mica, which is predicted to be a lysogenic myophage based on the similarity of its structural proteins to
James Garcia, Guichun Yao, Maria Guadalupe Vizoso-Pinto, James Clark, Tram Le, Carlos Gonzalez, Jason Gill, Mei Liu   +7 more
openaire   +3 more sources

Antibacterial properties of the pituitary adenylate cyclase-activating polypeptide: A new human antimicrobial peptide. [PDF]

PLoS ONE, 2018
The Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), a polycationic, amphiphilic and helical neuropeptide, is well known for its neuroprotective actions and cell penetrating properties.
Somia Debbabi, Marie-Christine Groleau, Myriam Létourneau, Chitra Narayanan, Laura-Lee Gosselin, Mustapha Iddir, Jacinthe Gagnon, Nicolas Doucet, Eric Déziel, David Chatenet   +9 more
doaj   +1 more source

Surface Motility Favors Codependent Interaction between Pseudomonas aeruginosa and Burkholderia cenocepacia

mSphere, 2022
Interactions between different bacterial species shape bacterial communities and their environments. The opportunistic pathogens Pseudomonas aeruginosa and Burkholderia cenocepacia both can colonize the lungs of individuals affected by cystic fibrosis ...
Charles Morin, May Landry, Marie-Christine Groleau, Eric Déziel   +3 more
doaj   +1 more source

Diversity of the parB and repA genes of the Burkholderia cepacia complex and their utility for rapid identification of Burkholderia cenocepacia [PDF]

, 2008
Background: Burkholderia cenocepacia is the most prominent species of the B. cepacia complex (Bcc), a group of nine closely related and difficult to identify bacteria that cause serious infections in patients with cystic fibrosis.
Mahenthiralingam Eshwar, Dowson, C. G., Pavel Drevinek, Adam Baldwin, Dowson, Christopher G., Dowson Christopher G, Christopher G Dowson, Drevinek, Pavel, Baldwin, A., Baldwin Adam, Baldwin, Adam, Drevinek, P., Drevinek Pavel, Eshwar Mahenthiralingam, Mahenthiralingam, Eshwar   +14 more
core   +1 more source