Results 41 to 50 of about 4,698 (167)

A unique regulator contributes to quorum sensing and virulence in Burkholderia cenocepacia. [PDF]

PLoS ONE, 2012
Burkholderia cenocepacia causes chronic and life-threatening respiratory infections in immunocompromized people. The B. cenocepacia N-acyl-homoserine lactone (AHL)-dependent quorum sensing system relies on the production of AHLs by the synthases CepI and
Eoin P O'Grady, Duber F Viteri, Pamela A Sokol   +2 more
doaj   +1 more source

Functional Analysis of the Burkholderia cenocepacia ZmpA Metalloprotease [PDF]

Journal of Bacteriology, 2005
ABSTRACT Burkholderia cenocepacia ZmpA is expressed as a preproenzyme typical of thermolysin-like proteases such as Pseudomonas aeruginosa LasB and Bacillus thermoproteolyticus thermolysin. The zmpA gene was expressed using the pPRO-EXHTa His
C, Kooi, C R, Corbett, P A, Sokol
openaire   +2 more sources

Prosthetic Joint Infection due to Burkholderia cenocepacia: An Opportunistic Pathogen Microbiology Section with an Expanding Spectrum of Disease [PDF]

Journal of Clinical and Diagnostic Research, 2017
Burkholderia cenocepacia is an opportunistic pathogen widespread in moist environments. It has been associated with lung infections, blood, skin and genitourinary tract infections.
Sujeesh Sebastian, Rajesh Malhotra, Rojaleen Das, Arti Kapil, Benu Dhawan   +4 more
doaj   +1 more source

Proteomics insights into the Burkholderia cenocepacia phosphorus stress response [PDF]

Environmental Microbiology, 2021
Summary The Burkholderia cepacia complex is a group of Burkholderia species that are opportunistic pathogens causing high mortality rates in patients with cystic fibrosis.
Holly Shropshire, Rebekah A. Jones, María M. Aguilo‐Ferretjans, David J. Scanlan, Yin Chen   +4 more
openaire   +3 more sources

Genome Wide Identification, Characterization and Evolutionary Analysis of T6SS in Burkholderia cenocepacia Strains [PDF]

International Journal Bioautomation
Pathogens of the Burkholderia genus are causing diseases in a diverse variety of hosts. After the discovery of T6SS, it was found to play a pivotal role in virulence and other pathogenicity factors in different pathogenic Burkholderia species.
Sardarni K. Raza, Muhammad Ibrahim, Kainaat, Afshan Farid, Sardar S. N. Khan, Aqsa Talat, Tayyaba Arzoo, Syeda I. Fatima, Abdul Waheed   +8 more
doaj   +1 more source

Metabolomic profiling of Burkholderia cenocepacia in synthetic cystic fibrosis sputum medium reveals nutrient environment-specific production of virulence factors

Scientific Reports, 2021
Infections by Burkholderia cenocepacia lead to life-threatening disease in immunocompromised individuals, including those living with cystic fibrosis (CF). While genetic variation in various B.
Olakunle A. Jaiyesimi, Andrew C. McAvoy, David N. Fogg, Neha Garg   +3 more
doaj   +1 more source

Optimized cumate toolkit for tunable protein expression during in vitro and in vivo studies of Burkholderia cenocepacia

Applied and Environmental Microbiology
Inducible gene expression is pivotal to dissect bacterial physiology and virulence mechanisms. Across the Burkholderia genus, a limited range of inducible systems currently exist that allow tight regulation.
Hamza Tahir, Kristian I. Karlic, Godfrey Mwiti, Nichollas E. Scott   +3 more
doaj   +1 more source

Genetic similarity of Burkholderia cenocepacia from cystic fibrosis patients

Brazilian Journal of Infectious Diseases, 2013
Burkholderia cenocepacia may cause serious infections in patients with cystic fibrosis, and this microorganism can be highly transmissible. Pulsed-field gel electrophoresis is widely used to study the dynamics of strain spread in cystic fibrosis patients.
Luana Pretto, Fernanda de-Paris, Alice Beatriz Mombach Pinheiro Machado, Andreza Francisco Martins, Afonso Luís Barth   +4 more
doaj   +1 more source

Exploring phage–host interactions in Burkholderia cepacia complex bacterium to reveal host factors and phage resistance genes using CRISPRi functional genomics and transcriptomics

Microbiology Spectrum
Complex interactions of bacteriophages with their bacterial hosts determine phage host range and infectivity. While phage defense systems and host factors have been identified in model bacteria, they remain challenging to predict in non-model bacteria ...
Ben Diaz, Rohan Krishna, Joseph S. Schoeniger, Catherine M. Mageeney   +3 more
doaj   +1 more source

Burkholderia cenocepacia Vaginal Infection in Patient with Smoldering Myeloma and Chronic Hepatitis C

Emerging Infectious Diseases, 2004
We report a case of a vaginal infection caused by a strain of Burkholderia cenocepacia. The strain was isolated from vaginal swab specimens from a 68-year-old woman with smoldering myeloma and chronic hepatitis C virus infection who was hospitalized for ...
Andrea Petrucca, Paola Cipriani, Rosa Sessa, Antonella Teggi, Rosalia Pustorino, Daniela Santapaola, Mauro Nicoletti   +6 more
doaj   +1 more source