Results 21 to 30 of about 4,698 (167)

Human Cryptic Host Defence Peptide GVF27 Exhibits Anti-Infective Properties against Biofilm Forming Members of the Burkholderia cepacia Complex

Pharmaceuticals, 2022
Therapeutic solutions to counter Burkholderia cepacia complex (Bcc) bacteria are challenging due to their intrinsically high level of antibiotic resistance.
Andrea Bosso, Rosa Gaglione, Rocco Di Girolamo, Edwin J. A. Veldhuizen, Pilar García-Vello, Salvatore Fusco, Valeria Cafaro, Maria Monticelli, Rosanna Culurciello, Eugenio Notomista, Angela Arciello, Elio Pizzo   +11 more
doaj   +1 more source

Invasion and biofilm formation of Burkholderia dolosa is comparable with Burkholderia cenocepacia and Burkholderia multivorans [PDF]

Journal of Cystic Fibrosis, 2007
Colonisation with Burkholderia cepacia complex pathogens has been associated with accelerated decline in cystic fibrosis (CF) patients. The two most common species among the CF community are Burkholderia cenocepacia and Burkholderia multivorans. However, Burkholderia dolosa has recently been causing concern due to its transmissibility and virulence in ...
Caraher, Emma, Duff, Caroline, Mullen, Tracy, Mc Keon, Suzanne, Murphy, Philip, Callaghan, Máire, McClean, Siobhán   +6 more
openaire   +3 more sources

Complete Genome Sequence of Burkholderia cenocepacia Phage Paku. [PDF]

Microbiol Resour Announc, 2022
Burkholderia cenocepacia is able to cause infections in cystic fibrosis patients. B. cenocepacia phage Paku has a 42,727-bp genome sharing a phiKMV-like genome arrangement. T7-like tail components were identified in parallel with a tyrosine integrase, suggesting that Paku might exhibit a temperate ...
Rezene S, Yao G, Le T, Burrowes B, Gonzalez C, Liu M, Gill J.   +6 more
europepmc   +3 more sources

Burkholderia cenocepacia utilizes ferritin as an iron source [PDF]

Journal of Medical Microbiology, 2006
Burkholderia cenocepaciais a member of theBurkholderia cepaciacomplex, a group of genetically similar species that inhabit a number of environmental niches, including the lungs of patients with cystic fibrosis (CF). To colonize the lung, this bacterium requires a source of iron to satisfy its nutritional requirements for this important metal.
Paul W, Whitby, Timothy M, VanWagoner, Jennifer M, Springer, Daniel J, Morton, Thomas W, Seale, Terrence L, Stull   +5 more
openaire   +2 more sources

Characterization of a bifunctional catalase–peroxidase ofBurkholderia cenocepacia [PDF]

FEMS Immunology & Medical Microbiology, 2007
Isolates of Burkholderia cenocepacia express a putative haem-binding protein (molecular mass 97 kDa) that displays intrinsic peroxidase activity. Its role has been re-evaluated, and we now show that it is a bifunctional catalase-peroxidase, with activity against tetramethylbenzidine (TMB), o-dianisidine, pyrogallol, and 2,2'-azino-bis(3 ...
Charalabous, Panagoula, Risk, Janet M, Jenkins, Rosalind, Birss, Andrew J, Hart, C Anthony, Smalley, John W   +5 more
openaire   +3 more sources

New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates

Antibiotics, 2021
Bacteria of the genus Burkholderia include pathogenic Burkholderia mallei, Burkholderia pseudomallei and the Burkholderia cepacia complex (Bcc). These Gram-negative pathogens have intrinsic drug resistance, which makes treatment of infections difficult ...
Dustin Maydaniuk, Bin Wu, Dang Truong, Sajani H. Liyanage, Andrew M. Hogan, Zhong Ling Yap, Mingdi Yan, Silvia T. Cardona   +7 more
doaj   +1 more source

Burkholderia cenocepaciaInduces Macropinocytosis to Enter Macrophages [PDF]

BioMed Research International, 2018
Burkholderia cenocepaciais an opportunistic pathogen that infects individuals with cystic fibrosis, chronic granulomatous disease, and other immunocompromised states.B. cenocepaciasurvives in macrophages in membrane-bound vacuoles; however, the mechanism by whichB. cenocepaciagains entry into macrophages remains unknown.
Roberto Rosales-Reyes, Concepción Sánchez-Gómez, Vianney Ortiz-Navarrete, José Ignacio Santos-Preciado   +3 more
openaire   +2 more sources

Complete Genome Sequence of Burkholderia cenocepacia Phage Mica

Microbiology Resource Announcements, 2021
Burkholderia cenocepacia is a multidrug-resistant Gram-negative pathogen known to colonize patients with chronic granulomatous disease and cystic fibrosis. Here, we describe Burkholderia phage Mica, which is predicted to be a lysogenic myophage based on the similarity of its structural proteins to
James Garcia, Guichun Yao, Maria Guadalupe Vizoso-Pinto, James Clark, Tram Le, Carlos Gonzalez, Jason Gill, Mei Liu   +7 more
openaire   +3 more sources

Burkholderia cenocepacia bacteremia in the oncology clinic: clinical features and outcomes

Журнал инфектологии, 2019
Aim of the study: To determine clinical course of Burkholderia cenocepacia bacteremia and outcomes in patients receiving cancer therapy. Materials and methods: We indentified 10 adult patients with culture-verified catheter-related Burkholderia ...
I. A. Kurmukov, A. M. Pronina, Sh. R. Kashiya, N. S. Bagirova, N. V. Dmitrieva, Z. V. Grigor’yevskaya, I. N. Petuhova, I. V. Tereshchenko   +7 more
doaj   +1 more source

First cases of Burkholderia cenocepacia IIIA neonatal sepsis in Central African Republic

The Pan African Medical Journal, 2020
Bacteria of the Burkholderia cepaciai complex cause frequent infections in immunocompromised and hospitalized patients, with a significant mortality rate.
Thierry Frank, Julita Gil-Cuesta, Jean Robert Mbecko, Hugues Sanke, Chantal Lakis, Anne Le Flèche-Matéos, Alain Berlioz-Arthaud   +6 more
doaj   +1 more source