Glycoproteomic and proteomic analysis of Burkholderia cenocepacia reveals glycosylation events within FliF and MotB are dispensable for motility [PDF]
Microbiology SpectrumAcross the Burkholderia genus O-linked protein glycosylation is highly conserved. While the inhibition of glycosylation has been shown to be detrimental for virulence in Burkholderia cepacia complex species, such as Burkholderia cenocepacia, little is ...
Nichollas E Scott +2 more
exaly +4 more sources
Oridonin Attenuates Burkholderia cenocepacia Virulence by Suppressing Quorum-Sensing Signaling [PDF]
Microbiology Spectrum, 2022 Burkholderia cenocepacia is a human opportunistic pathogen that mostly employs two types of quorum-sensing (QS) systems to regulate its various biological functions and pathogenicity: the cis-2-dodecenoic acid (BDSF) system and the N-acyl homoserine ...
Xia Li +6 more
doaj +2 more sources
A case of localized paranasal sinusitis associated with Burkholderia cenocepacia ST 1880 in a cystic fibrosis patient [PDF]
Heliyon, 2023 Burkholderia cepacia complex (Bcc) bacteria are considered to be very dangerous players in cystic fibrosis (CF) pathogenesis and are a criterion for negative prognosis in CF cases.
Olga Kondratenko +5 more
doaj +2 more sources
Phylogeny, Synteny, and Distribution of Type III Secretion Systems in Burkholderia cenocepacia: A Closer Look Into Host Span. [PDF]
MicrobiologyopenT3SS is a dedicated machinery that mediates interactions between bacteria and eukaryotic cells, providing a functional interface in pathogenic or symbiotic associations. Phylogenetic analyses and T3SS‐gene synteny revealed nine gene clusters, with no needle protein gene (sctF). However, an orphan CDS encoding a putative SctF was found.
Cordeiro GT +5 more
europepmc +2 more sources
Nebulized levofloxacin for chronic Burkholderia cenocepacia pulmonary infection in cystic fibrosis: A case report [PDF]
Respiratory Medicine Case Reports, 2022 We present a patient with cystic fibrosis who used nebulized levofloxacin off-label to suppress chronic Burkholderia cenocepacia pulmonary infection.
Renée VE. Dagenais +2 more
doaj +2 more sources
The Small RNA NcS25 Regulates Biological Amine-Transporting Outer Membrane Porin BCAL3473 in Burkholderia cenocepacia [PDF]
mSphere, 2023 Regulation of porin expression in bacteria is complex and often involves small-RNA regulators. Several small-RNA regulators have been described for Burkholderia cenocepacia, and this study aimed to characterize the biological role of the conserved small ...
Andrea M. Sass, Tom Coenye
doaj +2 more sources
Case Reports in Infectious DiseasesBurkholderia cenocepacia, a member of the Burkholderia cepacia complex (BCC), is an opportunistic, intrinsically multidrug-resistant Gram-negative bacillus most commonly associated with nosocomial outbreaks and chronic pulmonary infection in patients ...
Zhong Xhen Khor +3 more
doaj +2 more sources
Characterization of the Burkholderia cenocepacia TonB Mutant as a Potential Live Attenuated Vaccine
Vaccines, 2017 Burkholderia cenocepacia is an opportunistic pathogen prevalent in cystic fibrosis patients, which is particularly difficult to treat, causing chronic and eventually fatal infections.
Alfredo Torres +2 more
exaly +3 more sources
Phage-antibiotic synergy reduces Burkholderia cenocepacia population [PDF]
BMC Microbiology, 2023 Background Burkholderia cenocepacia is an opportunistic pathogen that can cause acute and chronic infections in patients with weakened immune systems and in patients with cystic fibrosis. B.
Anna G. Mankovich +5 more
doaj +2 more sources
Unraveling Burkholderia cenocepacia H111 fitness determinants using two animal models [PDF]
mSystemsBurkholderia cenocepacia is an opportunistic pathogen that has been associated with nosocomial outbreaks in hospitals and can cause severe respiratory infections among immunocompromised patients and individuals suffering from cystic fibrosis.
Sarah Paszti +5 more
doaj +2 more sources