Results 101 to 110 of about 22,503 (210)

Melioidosis Caused by Burkholderia pseudomallei in Drinking Water, Thailand, 2012

Emerging Infectious Diseases, 2014
We identified 10 patients in Thailand with culture-confirmed melioidosis who had Burkholderia pseudomallei isolated from their drinking water. The multilocus sequence type of B.
Direk Limmathurotsakul, Gumphol Wongsuvan, David Aanensen, Sujittra Ngamwilai, Natnaree Saiprom, Patpong Rongkard, Janjira Thaipadungpanit, Manas Kanoksil, Narisara Chantratita, Nicholas P.J. Day, Sharon J. Peacock   +10 more
doaj   +1 more source

The pathogen Pseudomonas aeruginosa negatively affects the attraction response of the nematode Caenorhabditis elegans to bacteria.

, 2006
The nematode Caenorhabditis elegans has previously been used to identify virulence mechanisms of bacteria and to characterise host responses to infection. In this study, we have developed an assay to measure C.
Atkins, Helen S, Atkins, Timothy P, Laws, Thomas R, Titball, Richard W   +3 more
core   +1 more source

Bioluminescent Diagnostic Imaging to Characterize Altered Respiratory Tract Colonization by the Burkholderia Pseudomallei Capsule Mutant [PDF]

, 2011
Pneumonia is a common manifestation of the highly fatal disease melioidosis, caused by the select agent bacteria Burkholderia pseudomallei. In this study we describe a new model system to investigate pulmonary melioidosis using bioluminescent-engineered ...
Jonathan Mark Warawa, Jonathan Mark Warawa, Dan eLong, Rebecca eRosenke, Don eGardner, Frank eGherardini   +5 more
core   +1 more source

TreC: A Critical Mediator of lysoPC‐Induced Hypervirulence in Streptococcus suis

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Streptococcus suis, a major zoonotic pathogen, employs diverse strategies to enhance virulence, yet the role of host‐derived metabolites in its pathogenicity remains underexplored. Here, we reveal a novel mechanism by which S. suis utilizes lysophosphatidylcholine (lysoPC), a host lipid signaling molecule, to enhance its virulence through treC ...
Xuefeng Cao, Jiajia Zheng, Song Xue, Qinyu Wei, Marc M. S. M. Wösten, Lianci Peng, Zhiwei Li, Rendong Fang, Anusak Kerdsin   +8 more
wiley   +1 more source

Absence of Yersinia pestis-specific DNA in human teeth from five European excavations of putative plague victims.

, 2004
This study reports the results of a collaborative study undertaken by two independent research groups to (a) confirm recent PCR-based detection of Yersinia pestis DNA in human teeth from medieval plague victims in France, and (b) to extend these ...
Cooper, Alan, Cuccui, Jon, Gilbert, M Thomas P, Lynnerup, Niels, Prentice, Michael B, Titball, Richard W, White, William   +6 more
core   +1 more source

Myd88-dependent recruitment of monocytes and dendritic cells required for protection from pulmonary Burkholderia mallei infection [PDF]

, 2012
The Gram-negative bacterium Burkholderia mallei causes rapidly fatal illness in equines and humans when contracted by inhalation and also has the potential to be used as a bioweapon.
Goodyear, Andrew, Troyer, Ryan, Bielefeldt-Ohmann, Helle, Dow, Steven   +3 more
core   +1 more source

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

Bacterial drug tolerance under clinical conditions is governed by anaerobic adaptation but not anaerobic respiration [PDF]

, 2016
This is the final version of the article. Available from the publisher via the DOI in this record.Noninherited antibiotic resistance is a phenomenon whereby a subpopulation of genetically identical bacteria displays phenotypic tolerance to antibiotics ...
Andreae, CA, Butler, CS, Hemsley, CM, Luo, JX, Soyer, OS, Titball, RW   +5 more
core   +1 more source

Phylogeny, Synteny, and Distribution of Type III Secretion Systems in Burkholderia cenocepacia: A Closer Look Into Host Span

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
T3SS is a dedicated machinery that mediates interactions between bacteria and eukaryotic cells, providing a functional interface in pathogenic or symbiotic associations. Phylogenetic analyses and T3SS‐gene synteny revealed nine gene clusters, with no needle protein gene (sctF). However, an orphan CDS encoding a putative SctF was found.
Gabrielle Tomé Cordeiro, Hadassa Loth de Oliveira, Danielly C. O. Mariano, Yasmin Salazar Torres, Graciela Maria Dias, Bianca C. Neves   +5 more
wiley   +1 more source

The condition-dependent transcriptional landscape of Burkholderia pseudomallei [PDF]

, 2016
This is the final version of the article. Available from the publisher via the DOI in this record.Burkholderia pseudomallei (Bp), the causative agent of the often-deadly infectious disease melioidosis, contains one of the largest prokaryotic genomes ...
Ang, RM, Bancroft, GJ, Chen, Y, Chua, HH, Conejero, L, Eshaghi, M, Gan, YH, Korbsrisate, S, Kreisberg, JF, Liu, J, Mueller, C, Nandi, T, Ong, C, Ooi, WF, Sobral, BW, Sun, G, Tan, P, Titball, RW, Valade, E   +18 more
core   +1 more source