Detection of Burkholderia thailandensis in Soil Samples, Suriname
Melioidosis, caused by the highly lethal pathogen Burkholderia pseudomallei, is emerging in North and South America. We studied soil samples in Suriname to determine endemicity of Burkholderia species. B. thailandensis was isolated, but B.
Jelmer Savelkoel +10 more
doaj +1 more source
Burkholderia Vaccines: Are We Moving Forward?
The genus Burkholderia consists of diverse species which includes both ‘friends’ and ‘foes’. Some of the ‘friendly’ Burkholderia spp. are extensively used in the biotechnological and agricultural industry for bioremediation and biocontrol.
Leang-Chung eChoh +7 more
doaj +1 more source
The identification and characterisation of novel antimicrobial targets in Burkholderia pseudomallei [PDF]
The bacterium Burkholderia pseudomallei causes the disease melioidosis, a significant public health threat in endemic regions and is a potential biowarfare agent.
Marshall, Laura Emma
core
Adherence of Burkholderia pseudomallei cells to cultured human epithelial cell lines is regulated by growth temperature. [PDF]
We have investigated the adherence of Burkholderia pseudomallei, cultured under a number of different conditions, to six human epithelial cell lines. While several complex medium compositions had relatively little effect on adherence, growth at 30àwas ...
Beacham, Ifor +3 more
core +2 more sources
Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco +24 more
wiley +1 more source
Interleukin 10 inhibits pro-inflammatory cytokine responses and killing of Burkholderia pseudomallei. [PDF]
Melioidosis, caused by Burkholderia pseudomallei, is endemic in northeastern Thailand and Northern Australia. Severe septicemic melioidosis is associated with high levels of pro-inflammatory cytokines and is correlated with poor clinical outcomes.
A Easton +54 more
core +1 more source
A comprehensive glycosylation study of diversely protected and activated d‐idopyranosyl and 6‐deoxy‐d‐ido‐heptopyranosyl donors using intra‐ and intermolecular coupling strategies is reported. Intramolecular aglycon delivery afforded 1,2‐cis‐β‐idopyranosides, while intermolecular glycosylation yielded chromatographically separable α‐ and β‐linked ...
Maude Cloutier +3 more
wiley +1 more source
Tracking melioidosis in Iran: Utilizing abattoir‐based surveillance as a One Health approach
Background Burkholderia pseudomallei, an environmental saprophyte bacterium, causes melioidosis in humans and animals. It was first discovered in Iran between 1967 and 1976 in small ruminants, equines, environments and humans.
Nader Mosavari +9 more
doaj +1 more source
Description of two fatal cases of melioidosis in Mexican children with acute pneumonia: case report
Background Melioidosis is an infectious disease caused by Burkholderia pseudomallei. In Mexico, the disease is rarely diagnosed in humans and there is no evidence of simultaneous environmental isolation of the pathogen.
Gerardo Alvarez-Hernandez +7 more
doaj +1 more source
Rapid identification of Burkholderia mallei and Burkholderia pseudomallei by intact cell Matrix-assisted Laser Desorption/Ionisation mass spectrometric typing [PDF]
BACKGROUND: Burkholderia (B.) pseudomallei and B. mallei are genetically closely related species. B. pseudomallei causes melioidosis in humans and animals, whereas B. mallei is the causative agent of glanders in equines and rarely also in humans.
Axel Karger +10 more
core +1 more source

