Results 111 to 120 of about 22,717 (216)

An objective approach for Burkholderia pseudomallei strain selection as challenge material for medical countermeasures efficacy testing [PDF]

, 2012
Burkholderia pseudomallei is the causative agent of melioidosis, a rare disease of biodefense concern with high mortality and extreme difficulty in treatment. No human vaccines are available that protect against B.
Gelhaus, H. Carl, Keim, Paul S., Tuanyok, Apichai, Van Zandt, Kristopher E., Warren, Richard L.   +4 more
core   +2 more sources

Burkholderia pseudomallei, the causative agent of melioidosis, is rare but ecologically established and widely dispersed in the environment in Puerto Rico.

PLoS Neglected Tropical Diseases, 2019
BackgroundBurkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of melioidosis. The global burden and distribution of melioidosis is poorly understood, including in the Caribbean. B.
Carina M Hall, Sierra Jaramillo, Rebecca Jimenez, Nathan E Stone, Heather Centner, Joseph D Busch, Nicole Bratsch, Chandler C Roe, Jay E Gee, Alex R Hoffmaster, Sarai Rivera-Garcia, Fred Soltero, Kyle Ryff, Janice Perez-Padilla, Paul Keim, Jason W Sahl, David M Wagner   +16 more
doaj   +1 more source

Continuing evolution of Burkholderia mallei through genome reduction and large-scale rearrangements [PDF]

, 2010
Burkholderia mallei (Bm), the causative agent of the predominately equine disease glanders, is a genetically uniform species that is very closely related to the much more diverse species Burkholderia pseudomallei (Bp), an opportunistic human pathogen and
Badger, Jonathan, Beckstrom-Sternberg, Stephen M., Brinkac, Lauren, Crabtree, Jonathan, DeShazer, David, Fedorova, Natalie, Keim, Paul, Kim, H. Stanley, Losada, Liliana, Nandi, Tannistha, Nierman, William C., Pearson, Talima R., Ronning, Catherine M., Saqib, Muhammad, Schutzer, Steven E., Shabalina, Svetlana A., Tan, Patrick, Woods, Donald   +17 more
core   +2 more sources

Burkholderia pseudomalleiMisidentified by Automated System

Emerging Infectious Diseases, 2009
After returning from Thailand, a 35-year-old man from Switzerland was hospitalized with an abscess of the head. Material cultured from the abscess and adjacent bone grew a gram-negative rod, which was misidentified by an automated microbiology system as Burkholderia cepacia. The organism was eventually identified by molecular methods as B. pseudomallei.
Christoph Weissert, Günter Dollenmaier, Philippe Rafeiner, Julia M. Riehm, Detlev Schultze   +4 more
openaire   +3 more sources

Multiplex qPCR for reliable detection and differentiation of Burkholderia mallei and Burkholderia pseudomallei

BMC Infectious Diseases, 2013
Background Burkholderia mallei and B. pseudomallei are two closely related species of highly virulent bacteria that can be difficult to detect. Pathogenic Burkholderia are endemic in many regions worldwide and cases of infection, sometimes brought by ...
Janse Ingmar, Hamidjaja Raditijo A, Hendriks Amber CA, van Rotterdam Bart J   +3 more
doaj   +1 more source

Sequence-Defined Transposon Mutant Library of Burkholderia thailandensis

mBio, 2013
We constructed a near-saturation transposon mutant library for Burkholderia thailandensis, a low-virulence surrogate for the causative agent of melioidosis (Burkholderia pseudomallei). A primary set of nearly 42,000 unique mutants (~7.5 mutants/gene) was
Larry A. Gallagher, Elizabeth Ramage, Rapatbhorn Patrapuvich, Eli Weiss, Mitch Brittnacher, Colin Manoil   +5 more
doaj   +1 more source

Trimethoprim/sulfamethoxazole resistance in Burkholderia pseudomallei

International Journal of Antimicrobial Agents, 2014
Sir, With the recent publication of the MERTH study [1], trimethoprim/sulfamethoxazole (SXT) monotherapy will be used increasingly in the treatment of melioidosis during the eradication phase, and possibly as the only treatment for some mild infections.
Dance, D, Davong, V, Soeng, S, Phetsouvanh, R, Newton, P, Turner, P   +5 more
openaire   +3 more sources

Burkholderia pseudomallei Evades Nramp1 (Slc11a1)- and NADPH Oxidase-Mediated Killing in Macrophages and Exhibits Nramp1-Dependent Virulence Gene Expression

Frontiers in Cellular and Infection Microbiology, 2017
Bacterial survival in macrophages can be affected by the natural resistance-associated macrophage protein 1 (Nramp1; also known as solute carrier family 11 member a1 or Slc11a1) which localizes to phagosome membranes and transports divalent cations ...
Veerachat Muangsombut, Patoo Withatanung, Varintip Srinon, Varintip Srinon, Narisara Chantratita, Mark P. Stevens, Jenefer M. Blackwell, Jenefer M. Blackwell, Sunee Korbsrisate   +8 more
doaj   +1 more source

BURKHOLDERIA PSEUDOMALLEI SEPTICAEMIA – A CASE REPORT

Indian Journal of Medical Microbiology, 2004
Burkholderia pseudomallei, a natural saprophyte widely distributed in soil, stagnant waters of endemic areas, is said to infect humans through breaks in the skin or through inhalation causing protean clinical manifestations including fatal septicaemia. A case of septicaemia in a elderly female diabetic due to B. pseudomallei following a history of fall
M, Dias, B, Antony, S, Aithala, B, Hanumanthappa, H, Pinto, B, Rekha   +5 more
openaire   +2 more sources

Burkholderia pseudomalleiAntibodies in Children, Cambodia

Emerging Infectious Diseases, 2008
Antibodies to Burkholderia pseudomallei were detected in 16% of children in Siem Reap, Cambodia. This organism was isolated from 30% of rice paddies in the surrounding vicinity. Despite the lack of reported indigenous cases, melioidosis is likely to occur in Cambodia.
Wuthiekanun, V, Pheaktra, N, Putchhat, H, Sin, L, Sen, B, Kumar, V, Langla, S, Peacock, S, Day, N   +8 more
openaire   +3 more sources