Results 1 to 10 of about 426,474 (189)

Burkitt-like lymphoma with 11q aberration: a germinal center-derived lymphoma genetically unrelated to Burkitt lymphoma

Haematologica, 2019
Burkitt-like lymphoma with 11q aberration is characterized by pathological features and gene expression profile resembling those of Burkitt lymphoma but lacks the MYC rearrangement and carries an 11q-arm aberration with proximal gains and telomeric ...
Blanca Gonzalez-Farre, Joan Enric Ramis-Zaldivar, Julia Salmeron-Villalobos, Olga Balagué, Verónica Celis, Jaime Verdu-Amoros, Ferran Nadeu, Constantino Sábado, Antonio Ferrández, Marta Garrido, Federico García-Bragado, María Dolores de la Maya, José Manuel Vagace, Carlos Manuel Panizo, Itziar Astigarraga, Mara Andrés, Elaine S. Jaffe, Elias Campo, Itziar Salaverria   +18 more
doaj   +2 more sources

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma

Haematologica, 2017
Inhibition of monocarboxylate transporter 1 has been proposed as a therapeutic approach to perturb lactate shuttling in tumor cells that lack monocarboxylate transporter 4.
Richard A. Noble, Natalie Bell, Helen Blair, Arti Sikka, Huw Thomas, Nicole Phillips, Sirintra Nakjang, Satomi Miwa, Rachel Crossland, Vikki Rand, Despina Televantou, Anna Long, Hector C. Keun, Chris M. Bacon, Simon Bomken, Susan E. Critchlow, Stephen R. Wedge   +16 more
doaj   +2 more sources

Diagnostic Delay in Pediatric Nasopharyngeal Burkitt Lymphoma Presenting With Chronic Otalgia and Multiple Cranial Nerve Palsies: A Case Report [PDF]

Clin Case Rep
ABSTRACT Persistent unilateral otalgia, especially when refractory to treatment and associated with cranial nerve signs, should prompt early imaging and nasopharyngeal evaluation to avoid delayed diagnosis of aggressive malignancies such as Burkitt lymphoma.
Haddad S, Al‐Shaikhli A, Hallak F, Hamdan H, Farag A, Nakhal R, Alramdani S, Alsadi M, Hamza R, Hamdan O.   +9 more
europepmc   +2 more sources

Paraneoplastic Myopathy as a Possible Initial Presentation of Sporadic Burkitt Lymphoma in an Immunocompetent Adult: A Case Report. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Burkitt's lymphoma (BL) is a highly aggressive B‐cell non‐Hodgkin lymphoma with rapid proliferation and early systemic dissemination. Neuromuscular manifestations are rare and are typically secondary to direct infiltration or metabolic complications.
Khalafi-Nezhad A, Firouzabadi D, Mohammadkarimi V, Dehghanian A.   +3 more
europepmc   +2 more sources

Single-cell whole-genome sequencing reveals convergent evolution in Burkitt lymphoma [PDF]

Nature Communications
Burkitt lymphoma carries multiple oncogenic drivers yet arises predominantly in children, whose normal cells harbour few age-related mutations. To investigate this paradox, we seek to define the sequence and timing of mutational drivers underlying ...
Alexander S. Steemers, Markus J. van Roosmalen, Rico Hagelaar, Laurianne Trabut, Mark Verheul, Jurrian K. de Kanter, Siem Jongsma, Lucca L. M. Derks, Alexander R. Blackwell, Friederike Meyer-Wentrup, Ruben van Boxtel   +10 more
doaj   +2 more sources

The Growth Supporting Role of ZDHHC11 Is Linked to the MEF2B-BCL6 Regulatory Circuit in Burkitt Lymphoma. [PDF]

Int J Cancer
MEF2B and BCL6 have established functions in germinal center B‐cell biology and lymphomagenesis. The mechanism of MEF2B deregulation and its significance for cell survival in Burkitt lymphoma however remain unclear. This study highlights MEF2B as a crucial transcription factor in Burkitt lymphoma and suggests ZDHHC11 as an upstream regulator of MEF2B ...
Ziel-Swier LJYM, Rassek K, Liu Y, Seitz A, Koerts J, de Jong D, Rutgers B, Kompaniiets A, Przybył J, Chamuleau MED, van den Berg A, Dzikiewicz-Krawczyk A, Kluiver J.   +12 more
europepmc   +2 more sources

Burkitt Lymphoma Presentation with Oropharyngeal Mass of Tonsillar Fossa: A Case Report [PDF]

Clinical Practice and Cases in Emergency Medicine
Introduction: Burkitt lymphoma is a highly aggressive subtype of non-Hodgkin lymphoma with varied clinical presentation, including in some cases involvement of the intraoral cavity.
Diormi A. Rosario, Stephanie Aronson, Jessica Zerzan   +2 more
doaj   +2 more sources

Burkitt Lymphoma International Prognostic Index.

Journal of Clinical Oncology, 2021
PURPOSE Burkitt lymphoma (BL) has unique biology and clinical course but lacks a standardized prognostic model. We developed and validated a novel prognostic index specific for BL to aid risk stratification, interpretation of clinical trials, and ...
A. Olszewski, L. Jakobsen, G. Collins, K. Cwynarski, V. Bachanova, K. Blum, K. Boughan, M. Bower, Alessia Dalla Pria, A. Danilov, K. David, C. Diefenbach, F. Ellin, N. Epperla, U. Farooq, T. Feldman, A. Gerrie, D. Jagadeesh, M. Kamdar, Reem Karmali, S. Kassam, V. Kenkre, N. Khan, Seo-Hyun Kim, A. Klein, I. Lossos, Matthew A. Lunning, P. Martin, N. Martínez-Calle, S. Montoto, S. Naik, N. Palmisiano, D. Peace, E. Phillips, T. Phillips, C. Portell, N. Reddy, A. Santarsieri, Maryam Sarraf Yazdy, K. Smeland, Scott E. Smith, Stephen D. Smith, S. Sundaram, A. Zayac, Xiao-Yin Zhang, Catherine Zhu, Che-Ah Y. Chan, T. El-Galaly, A. Evens   +48 more
semanticscholar   +1 more source

Sequential different B-cell antigen–targeted CAR T-cell therapy for pediatric refractory/relapsed Burkitt lymphoma

Blood Advances, 2021
Key Points Sequential CAR T-cell therapy may result in a durable response and is safe in pediatric patients with R/R Burkitt lymphoma. Sequential CAR T-cell therapy may benefit pediatric patients with R/R Burkitt lymphoma with CNS involvement.
Ying Liu, B. Deng, Bo Hu, Wenqun Zhang, Qing Zhu, Yang Liu, Shanshan Wang, Pei Zhang, Ying Yang, Junhan Yang, Qinlong Zheng, Xinjian Yu, Zi-Fen Gao, Chunju Zhou, W. Han, Jing Yang, Ling Jin, C. Tong, Alex H. Chang, Yonghong Zhang   +19 more
semanticscholar   +1 more source

Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa

Nature Communications, 2023
In high-income countries, mosaic chromosomal alterations in peripheral blood leukocytes are associated with an elevated risk of adverse health outcomes, including hematologic malignancies.
Weiyin Zhou, Anja Fischer, Martin D. Ogwang, Wen Luo, Patrick Kerchan, Steven J. Reynolds, Constance N. Tenge, Pamela A. Were, Robert T. Kuremu, Walter N. Wekesa, Nestory Masalu, Esther Kawira, Tobias Kinyera, Isaac Otim, Ismail D. Legason, Hadijah Nabalende, Leona W. Ayers, Kishor Bhatia, James J. Goedert, Mateus H. Gouveia, Nathan Cole, Belynda Hicks, Kristine Jones, Michael Hummel, Mathias Schlesner, George Chagaluka, Nora Mutalima, Eric Borgstein, George N. Liomba, Steve Kamiza, Nyengo Mkandawire, Collins Mitambo, Elizabeth M. Molyneux, Robert Newton, Selina Glaser, Helene Kretzmer, Michelle Manning, Amy Hutchinson, Ann W. Hsing, Yao Tettey, Andrew A. Adjei, Stephen J. Chanock, Reiner Siebert, Meredith Yeager, Ludmila Prokunina-Olsson, Mitchell J. Machiela, Sam M. Mbulaiteye   +46 more
doaj   +1 more source