Results 161 to 170 of about 24,412 (262)

Mechanisms of Induction of Stimulus-Specific Systemic Responses of Photosynthesis in Wheat Plants. [PDF]

Int J Mol Sci
Mudrilov M, Ladeynova M, Pirogova P, Kuznetsova D, Obydennova S, Vodeneev V.   +5 more
europepmc   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

CO₂ Hydrogenation Using Nonthermal Plasma: Effects of Packed Beds on Plasma Discharge Behavior. [PDF]

Ind Eng Chem Res
Perera SM, Ekinci B, Bilén SG, Knecht SD, Noh G.   +4 more
europepmc   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Comparison of platelet rich plasma and injectable steroids in the treatment of oral lichen planus: A systematic review and meta-analysis. [PDF]

Natl J Maxillofac Surg
Kumar A, Srivastava A, Sah N, Shekhar A, Darjee S, Shukla S, Singh A, Jadhav SK, Sah S.   +8 more
europepmc   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Diabetic Retinopathy in Bahraini Primary Care: A Cross-Sectional Study of Prevalence and Clinical Predictors. [PDF]

Cureus
Alawainati M, AlGhareeb N, Alhouli R, Buhejji M, Mohammad HF, AlBuainain H, Daraj LR, Alqallaf A, Almulla A, Alenezi W.   +9 more
europepmc   +1 more source

Integrated Engineering of CAR‐T Cells for Solid Tumours

Cell Proliferation, EarlyView.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang, Tan Li, Ping He, Zhijie Zhao, Shenglong Li, Liming Wang   +5 more
wiley   +1 more source

Transport studies of burning plasmas

九州大学応用力学研究所所報, 2000
TATEISHI, Gonta, ITOH, Sanae-I., YAGI, Masatoshi   +2 more
openaire   +2 more sources

Accessing the density-free regime with ECRH-assisted ohmic start-up on EAST. [PDF]

Sci Adv
Liu J, Zhu P, Escande DF, Liu W, Xue S, Lin X, Tang P, Wang L, Yan N, Yang J, Duan Y, Jia K, Wu Z, Cheng Y, Zhang L, Qian J, Ding R, Zhou R, EAST team.   +18 more
europepmc   +1 more source