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Bursa of Fabricius and Immunological Tolerance
Nature, 1968TRANSIENT and nonspecific suppression of antibody production can be induced in chickens by neonatal removal of the bursa of Fabricius1. The role of the bursa in the initiation and maintenance of specific immunological tolerance (paralysis, unresponsiveness)2, and the characteristic features of tolerant bursaless birds, however, have not been ...
B D, Janković, K, Isaković, J, Horvat
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Lymphocyte-Differentiating Hormone of Bursa of Fabricius
Science, 1976Induction of early lymphocyte differentiation was studied in vitro in fractionated bone marrow cells of newly hatched chickens, with alloantiserums to identify newly differentiated B cells (Bu-1 + ) and T cells (Th-1 + ).
A, Brand, D G, Gilmour, G, Goldstein
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Cryptosporidiosis of the Bursa of Fabricius of Chickens
Avian Diseases, 1975Light-microscope and electron-microscope studies of a coccidial organism found in the bursa of Fabricius from 3 chickens clearly established the parasite as belonging to the family Cryptosporiidae. Hyperplasia and heterophil infiltration were associated with the presence of organisms attached to the microvillus border of epithelial cells lining the ...
O J, Fletcher, J F, Munnell, R K, Page
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Vasculogenesis of the bursa cloacalis (bursa of Fabricius) of the chick embryo
Journal of Morphology, 1981AbstractVasculogenesis of the bursa cloacalis (bursa of Fabricius) was examined in 10‐ to 21‐day chick embryos and in chicks during the first 5 days post‐hatching. The entire circulatory system was injected with India ink, and the bursae were then removed and either cleared for examination in toto or sectioned serially.
G C, Schoenwolf +2 more
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Histomoniasis in the Bursa of Fabricius of Chickens
Avian Diseases, 2004Histomoniasis was diagnosed in a flock of 6-wk-old commercial chickens. Clinical signs included depression, stilted gait, inappetence, and a slight increase in mortality. At necropsy, there were pale-yellow to dark-gray circular and depressed necrotic lesions in the liver. The ceca were enlarged and impacted with caseous cores.
Portia L, Cortes +4 more
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Bursa of Fabricius in Chickens: Possible Humoral Factor
Science, 1965Chicks bursectomized by testosterone injection on the 5th day of incubation showed a marked inability to produce antibodies to Salmonella typhimurium . When portions of the bursa of Fabricius were enclosed in cell-impermeable Millipore diffusion chambers and implanted subcutaneously or intraperitoneally, the ...
R L, STPIERRE, G A, ACKERMAN
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Ontogenic restriction of colonization of the bursa of Fabricius
European Journal of Immunology, 1983AbstractThe capacity of hemopoietic precursor cells (HPC) to home to embryonic bursal and thymic grafts was investigated in embryonic and newly hatched chickens. Whereas thymic grafts developed normal histogenesis in both types of recipients, the bursal rudiment was colonized and developed in embryonic, but not in newly hatched hosts.
E, Houssaint, A, Toraño, J, Ivanyi
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Epithelium of the Bursa of Fabricius Mucosa
Anatomia, Histologia, Embryologia, 2005The structure and topography of the Bursa of Fabricius (BF) differs from other central immune organs. Structural components, providing BF function are located in mucosa, which is constantly influenced by antigen stimulation. Therefore the reports, which have appeared recently, indicate that BF may function as a peripheral immune organ.
V. Khomych +3 more
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In vitro organ culture of embryonic bursa of fabricius
Developmental & Comparative Immunology, 1990An in vitro method for organ culture of embryonic bursa of Fabricius is presented. It is shown that bursa cells proliferate in in vitro culture as evidenced by [3H]-thymidine incorporation. We assessed the expression of B-cell alloantigen (Bu-la and Bu-lb), class I (B-F) and class II (B-L) antigens of chicken major histocompatibility complex (MHC), and
J S, Nowak, O, Vainio, O, Lassila
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Uptake of environmental antigens by the bursa of Fabricius
Nature, 1975THE bursa of Fabricius of birds has an essential role as a central lymphoid organ for the differentiation of B lymphocytes1,2. In addition, the bursa harbours immunocompetent B cells3 which are capable of local antibody production. Haemolytic plaque-forming cells have been observed in the bursa after introducing sheep red blood cells (SRBC) into the ...
T, Sorvari +4 more
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