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Uptake of environmental antigens by the bursa of Fabricius

Nature, 1975
THE bursa of Fabricius of birds has an essential role as a central lymphoid organ for the differentiation of B lymphocytes1,2. In addition, the bursa harbours immunocompetent B cells3 which are capable of local antibody production. Haemolytic plaque-forming cells have been observed in the bursa after introducing sheep red blood cells (SRBC) into the ...
T, Sorvari   +4 more
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Bursa of Fabricius in Chickens: Possible Humoral Factor

Science, 1965
Chicks bursectomized by testosterone injection on the 5th day of incubation showed a marked inability to produce antibodies to Salmonella typhimurium . When portions of the bursa of Fabricius were enclosed in cell-impermeable Millipore diffusion chambers and implanted subcutaneously or intraperitoneally, the ...
R L, STPIERRE, G A, ACKERMAN
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A MAMMALIAN EQUIVALENT OF THE AVIAN BURSA OF FABRICIUS

The Lancet, 1966
M D, Cooper   +5 more
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Bursa of Fabricius and Immunological Tolerance

Nature, 1968
TRANSIENT and nonspecific suppression of antibody production can be induced in chickens by neonatal removal of the bursa of Fabricius1. The role of the bursa in the initiation and maintenance of specific immunological tolerance (paralysis, unresponsiveness)2, and the characteristic features of tolerant bursaless birds, however, have not been ...
B D, Janković, K, Isaković, J, Horvat
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Lymphocyte-Differentiating Hormone of Bursa of Fabricius

Science, 1976
Induction of early lymphocyte differentiation was studied in vitro in fractionated bone marrow cells of newly hatched chickens, with alloantiserums to identify newly differentiated B cells (Bu-1 + ) and T cells (Th-1 + ).
A, Brand, D G, Gilmour, G, Goldstein
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Cryptosporidiosis of the Bursa of Fabricius of Chickens

Avian Diseases, 1975
Light-microscope and electron-microscope studies of a coccidial organism found in the bursa of Fabricius from 3 chickens clearly established the parasite as belonging to the family Cryptosporiidae. Hyperplasia and heterophil infiltration were associated with the presence of organisms attached to the microvillus border of epithelial cells lining the ...
O J, Fletcher, J F, Munnell, R K, Page
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