Results 21 to 30 of about 1,175 (147)
Bursicon-α subunit modulates dLGR2 activity in the adult Drosophila melanogaster midgut independently to Bursicon-β [PDF]
Cell Cycle, 2016 Bursicon is the main regulator of post molting and post eclosion processes during arthropod development. The active Bursicon hormone is a heterodimer of Burs-α and Burs-β. However, adult midguts express Burs-α to regulate the intestinal stem cell niche.
Alessandro Scopelliti +3 more
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Relish2 mediates bursicon homodimer-induced prophylactic immunity in the mosquito Aedes aegypti [PDF]
Scientific Reports, 2017 AbstractBursicon is a neuropeptide hormone consisting of two cystine-knot proteins (burs α and burs β), responsible for cuticle tanning and other developmental processes in insects. Recent studies show that each bursicon subunit forms homodimers that induce prophylactic immunity in Drosophila melanogaster.
Hongwei Zhang +6 more
openalex +3 more sources
Developmental Biology, 2010 Bursicon is an insect neuropeptide hormone that is secreted from the central nervous system into the hemolymph and initiates cuticle tanning. The receptor for bursicon is encoded by the rickets (rk) gene and belongs to the G protein-coupled receptor (GPCR) superfamily.
Hua Bai, Subba Reddy Palli
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Global identification of bursicon-regulated genes in Drosophila melanogaster
, 2019 Abstract Background Bursicon is a heterodimer neuropeptide responsible for regulating cuticle sclerotization and wing expansion in several insect species. Recent studies indicate that the action of bursicon is mediated by a specific G protein-coupled receptor DLGR2 and the cAMP/PKA signaling pathway.
Gilbert, Lawrence I
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On the origins and evolution of trans-splicing of bursicon in mosquitos [PDF]
, 2016 Broad transcriptomic sequencing of eukaryotes has revealed the ubiquity of splicing of nuclear genes. While the vast majority of splicing events join segments of the same RNA transcript, various studies have found a few intriguing cases of trans-splicing of introns, in which splicing events within protein coding regions join segments of different RNA ...
Scott William Roy
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Journal of Insect Physiology, 2016 Bursicon is the main regulator of post molting and post eclosion processes during arthropod development. The active Bursicon hormone is a heterodimer of Burs-α and Burs-β. However, adult midguts express Burs-α to regulate the intestinal stem cell niche.
Dušan Žitňan, Ivana Daubnerová
openaire +3 more sources
The essential role of bursicon during Drosophiladevelopment [PDF]
BMC Developmental Biology, 2010 Abstract Background The protective external cuticle of insects does not accommodate growth during development. To compensate for this, the insect life cycle is punctuated by a series of molts. During the molt, a new and larger cuticle is produced underneath the old cuticle.
Brandon Loveall, David L. Deitcher
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Neuromodulation and the toolkit for behavioural evolution: can ecdysis shed light on an old problem? [PDF]
FEBS JAltered neuromodulatory signalling via GPCRs frequently underlies evolutionary changes in behaviour. GPCRs and their ligands might thus represent a ‘toolkit’ akin to the Evo‐Devo toolkit responsible for animal development. Just as evolutionary changes in the Evo‐Devo toolkit can alter gene regulatory network function and morphology, changes in ...
Sullivan LF +4 more
europepmc +2 more sources
Journal of Comparative Physiology A, 2008 Bursicon was identified in 1965 as a peptide neurohormone that initiates the tanning of the insect cuticle immediately after the shedding of the old one during the final stages of the molting process. Its molecular identity as an approximately 30 kDa bioactive heterodimer consisting of two cystine knot proteins resisted elucidation for 43 years.
Hans‐Willi Honegger +2 more
openalex +6 more sources
Ecdysis‐related neuropeptide expression and metamorphosis in a non‐ecdysozoan bilaterian
Evolution, Volume 75, Issue 9, Page 2237-2250, September 2021., 2021 Abstract Ecdysis‐related neuropeptides (ERNs), including eclosion hormone, crustacean cardioactive peptide, myoinhibitory peptide, bursicon alpha, and bursicon beta regulate molting in insects and crustaceans. Recent evidence further revealed that ERNs likely play an ancestral role in invertebrate life cycle transitions, but their tempo‐spatial ...
Elisabeth Zieger +4 more
wiley +1 more source