Current Research in Insect Science, 2021 Insect neuropeptides, play a central role in the control of many physiological processes. Based on an analysis of Nyssorhynchus albimanus brain transcriptome a neuropeptide precursor database of the mosquito was described.
Alejandro Alvarado-Delgado +9 more
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Transcriptomic identification of starfish neuropeptide precursors yields new insights into neuropeptide evolution [PDF]
Open Biology, 2016 Neuropeptides are evolutionarily ancient mediators of neuronal signalling in nervous systems. With recent advances in genomics/transcriptomics, an increasingly wide range of species has become accessible for molecular analysis.
Dean C. Semmens +5 more
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Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2 [PDF]
FEBS Letters, 2005 Bursicon is a neurohumoral agent responsible for tanning and hardening of the cuticle and expansion of the wings during the final phase of insect metamorphosis. Although the hormonal activity was described more than 40 years ago, the molecular nature of bursicon has remained elusive.
Fernando Mendive +8 more
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Signaling Pathways That Regulate the Crustacean Molting Gland
Frontiers in Endocrinology, 2021 A pair of Y-organs (YOs) are the molting glands of decapod crustaceans. They synthesize and secrete steroid molting hormones (ecdysteroids) and their activity is controlled by external and internal signals.
Donald L. Mykles, Donald L. Mykles
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Rescheduling Behavioral Subunits of a Fixed Action Pattern by Genetic Manipulation of Peptidergic Signaling. [PDF]
PLoS Genetics, 2015 The ecdysis behavioral sequence in insects is a classic fixed action pattern (FAP) initiated by hormonal signaling. Ecdysis triggering hormones (ETHs) release the FAP through direct actions on the CNS.
Do-Hyoung Kim +5 more
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Insulin signaling regulates neurite growth during metamorphic neuronal remodeling
Biology Open, 2013 Summary Although the growth capacity of mature neurons is often limited, some neurons can shift through largely unknown mechanisms from stable maintenance growth to dynamic, organizational growth (e.g. to repair injury, or during development transitions).
Tingting Gu, Tao Zhao, Randall S. Hewes
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Frontiers in Neural Circuits, 2013 Peptidergic neurons are not easily integrated into current connectomics concepts, since their peptide messages can be distributed via non-synaptic paracrine signalling or volume transmission.
Gergely eKarsai +11 more
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Neuropeptidergic Signaling in the American Lobster Homarus americanus: New Insights from High-Throughput Nucleotide Sequencing. [PDF]
PLoS ONE, 2015 Peptides are the largest and most diverse class of molecules used for neurochemical communication, playing key roles in the control of essentially all aspects of physiology and behavior.
Andrew E Christie +7 more
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Peripheral Neurosecretory Cells of Insects Contain a Neuropeptide with Bursicon-Like Activity [PDF]
Journal of Experimental Biology, 1989 ABSTRACT In insects, neurosecretory cells have been found not only within ganglia of the central and stomatogastric nervous system, but also in the peripheral nerves (Fifield & Finlayson, 1978; Wasserman, 1985; Baudry-Partiaoglou, 1987).
Isabel Garcia-Scheible +1 more
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Ancient origins of arthropod moulting pathway components
eLife, 2019 Ecdysis (moulting) is the defining character of Ecdysoza (arthropods, nematodes and related phyla). Despite superficial similarities, the signalling cascade underlying moulting differs between Panarthropoda and the remaining ecdysozoans.
André Luiz de Oliveira +2 more
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