Results 51 to 60 of about 1,175 (147)

A fly's view of neuronal remodeling

WIREs Developmental Biology, Volume 5, Issue 5, Page 618-635, September/October 2016., 2016
Developmental neuronal remodeling is a crucial step in sculpting the final and mature brain connectivity in both vertebrates and invertebrates. Remodeling includes degenerative events, such as neurite pruning, that may be followed by regeneration to form novel connections during normal development.
Shiri P. Yaniv, Oren Schuldiner
wiley   +1 more source

Transcriptome of the female synganglion of the black-legged tick Ixodes scapularis (Acari: Ixodidae) with comparison between Illumina and 454 systems. [PDF]

PLoS ONE, 2014
Illumina and 454 pyrosequencing were used to characterize genes from the synganglion of female Ixodes scapularis. GO term searching success for biological processes was similar for samples sequenced by both methods.
Noble Egekwu, Daniel E Sonenshine, Brooke W Bissinger, R Michael Roe   +3 more
doaj   +1 more source

Drosophila Models of Tauopathies: What Have We Learned?

International Journal of Alzheimer’s Disease, Volume 2012, Issue 1, 2012., 2012
Aggregates of the microtubule‐associated protein Tau are neuropathological hallmark lesions in Alzheimer′s disease (AD) and related primary tauopathies. In addition, Tau is genetically implicated in a number of human neurodegenerative disorders including frontotemporal dementia (FTD) and Parkinson′s disease (PD). The exact mechanism by which Tau exerts
Marc Gistelinck, Jean-Charles Lambert, Patrick Callaerts, Bart Dermaut, Pierre Dourlen, David Blum   +5 more
wiley   +1 more source

TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila

Cell Reports, 2013
TDP-43 proteinopathy is strongly implicated in the pathogenesis of amyotrophic lateral sclerosis and related neurodegenerative disorders. Whether TDP-43 neurotoxicity is caused by a novel toxic gain-of-function mechanism of the aggregates or by a loss of
Lies Vanden Broeck, Marina Naval-Sánchez, Yoshitsugu Adachi, Danielle Diaper, Pierre Dourlen, Julien Chapuis, Gernot Kleinberger, Marc Gistelinck, Christine Van Broeckhoven, Jean-Charles Lambert, Frank Hirth, Stein Aerts, Patrick Callaerts, Bart Dermaut   +13 more
doaj   +1 more source

Transcriptome and peptidome characterisation of the main neuropeptides and peptidic hormones of a euphausiid: the Ice Krill, Euphausia crystallorophias. [PDF]

PLoS ONE, 2013
BACKGROUND: The Ice krill, Euphausia crystallorophias is one of the species at the base of the Southern Ocean food chain. Given their significant contribution to the biomass of the Southern Ocean, it is vitally important to gain a better understanding of
Jean-Yves Toullec, Erwan Corre, Benoît Bernay, Michael A S Thorne, Kévin Cascella, Céline Ollivaux, Joël Henry, Melody S Clark   +7 more
doaj   +1 more source

Ecdysis-related pleiotropic neuropeptides expression during Anopheles albimanus development

Salud Pública de México, 2017
Objective. To analyze the transcription pattern of neuropeptides in the ontogeny of a malaria vector, the mosquito Anopheles albimanus. Materials and methods.
Alejandro Alvarado-Delgado, Ken Moran-Francia, Guillermo Perales-Ortiz, Mario Henry Rodríguez, Humberto Lanz-Mendoza   +4 more
doaj   +1 more source

Two Splice Isoforms of Leptinotarsa Ecdysis Triggering Hormone Receptor Have Distinct Roles in Larva-Pupa Transition

Frontiers in Physiology, 2020
Insect ecdysis triggering hormone (ETH) receptors (ETHRs) are rhodopsin-like G protein-coupled receptors. Upon binding its ligand ETH, ETHR initiates a precisely programed ecdysis behavior series and physiological events.
Chen-Hui Shen, Qing-Yu Xu, Kai-Yun Fu, Wen-Chao Guo, Lin Jin, Guo-Qing Li   +5 more
doaj   +1 more source

From bioassays toDrosophilagenetics: Strategies for characterizing an essential insect neurohormone, bursicon [PDF]

Acta Biologica Hungarica, 2004
We describe the molecular analysis and cellular expression of the insect peptide neurohormone, bursicon. Bursicon triggers the sclerotization of the soft insect cuticle after ecdysis. Using protein elution analyses from SDS gels, we determined the molecular weight of bursicon from different insects to be approximately 30 kDa.
Hans‐Willi Honegger, Elizabeth M. Dewey, Barbara Kostron   +2 more
openalex   +4 more sources

Amino acid sequence coevolution in the insect bursicon ligand–receptor system [PDF]

Molecular Phylogenetics and Evolution, 2012
The pattern of amino acid residue replacement in the components of the bursicon signaling system (involving the BURSα/BURSβ heterodimer and its receptor BURSrec) was reconstructed across a phylogeny of 17 insect species, in order to test for the co-occurrence of replacements at sets of individual sites.
openaire   +2 more sources

The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B

Biology Open, 2015
During development, HOX genes play critical roles in the establishment of segmental differences. In the Drosophila central nervous system, these differences are manifested in the number and type of neurons generated by each neuroblast in each segment ...
M. Moris-Sanz, A. Estacio-Gómez, E. Sánchez-Herrero, F. J. Díaz-Benjumea   +3 more
doaj   +1 more source