Results 141 to 150 of about 1,472,869 (283)

Human inborn errors of the phagocyte respiratory burst: Chronic granulomatous disease and beyond. [PDF]

J Hum Immun
Neehus AL, Sankaran VG, Casanova JL, Bustamante J.   +3 more
europepmc   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Genomic and functional divergence analysis of closely related <i>Teseptimavirus</i> phages reveals dual HNH endonuclease positioning and its role in plaque formation. [PDF]

Appl Environ Microbiol
Yang X, Zheng S, Zhou B, Li S, Smidt H, Zhu W, Lin Y.   +6 more
europepmc   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source

Image-guided focused ultrasound for non-invasive modulation of superficial and deep tissues. [PDF]

STAR Protoc
Sangwan N, Chaggares NC, Torbatian Z, Anderson TA.   +3 more
europepmc   +1 more source

Round-Robin Burst Assembly and Constant Transmission Scheduling for Optical Burst Switching Networks

, 2007
In this paper, we propose a round-robin burst assembly and constant burst transmission for optical burst switching (OBS) network. In the proposed method, ingress edge node has multiple buffers where IP packets are stored depending on their egress edge ...
Shoji Kasahara, Takuji Tachibana, Tomoya Ajima   +2 more
core  

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source

Polymer extrusion filter remaining useful life dataset from contamination experiments. [PDF]

Data Brief
Ferreira C, Ko B, Li W, Otto K.
europepmc   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

AIRE transcriptional condensates in central tolerance: a multiscale mechanistic perspective. [PDF]

Front Immunol
He J, Xue W, Zhang J, Li Y.
europepmc   +1 more source