Results 121 to 130 of about 1,472,869 (283)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

A Sudden Fine-scale Bright Kernel Captured by Hi-C Flare in 11 MK Emission during an M1.6-class Solar Flare’s Postmaximum Phase

The Astrophysical Journal Letters
On 2024 April 17, the third successful Hi-C sounding rocket flight, Hi-C Flare, recorded coronal images in Fe XXI 129 Å emission from 11 MK plasma during the postmaximum phase of an M1.6-class solar flare, achieving unprecedented spatial (∼300 km) and ...
Sanjiv K. Tiwari, Navdeep K. Panesar, Ronald L. Moore, Sabrina L. Savage, Amy R. Winebarger, Genevieve D. Vigil, Juraj Lörinčík, Vanessa Polito, Bart De Pontieu, Leon Golub, Ken Kobayashi, Patrick Champey, Jenna Samra, Anna Rankin, Robert W. Walsh, Crisel Suarez, Christopher S. Moore, Adam R. Kobelski, Jeffrey W. Reep, Charles Kankelborg   +19 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Telomere-to-telomere genome assembly of Oryza australiensis reveals transposon-driven centromere repositioning and shared EE–DD ancestry

Nature Communications
Oryza australiensis (EE genome), the sole representative of the EE genome in the genus, holds significant value for deciphering polyploid evolution and mining stress-resistance genes owing to its extreme environmental adaptability.
Yu Bao, Hanli You, Shuo Liu, Guanqing Liu, Yuechao Wu, Qingqing Yang, Qi You, Peng Liu, Chuandeng Yi, Wenli Zhang, Zhukuan Cheng, Tao Zhang   +11 more
doaj   +1 more source

Round-robin burst assembly and constant transmission scheduling for optical burst switching networks [PDF]

, 2003
In this paper, we propose a round-robin burst assembly and constant burst transmission for optical burst switching (OBS) network. In the proposed method, ingress edge node has multiple buffers where IP packets are stored depending on their egress edge ...
Tachibana, Takuji, Ajima, Tomoya, 81, Kasahara, Shoji, 21943, 21942, 20263139   +6 more
core  

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Personalized Human Astrocyte‐Derived Region‐Specific Forebrain Organoids Recapitulate Endogenous Pathological Features of Focal Cortical Dysplasia

Advanced Science
Focal cortical dysplasia (FCD) is a highly heterogeneous neurodevelopmental malformation, the underlying mechanisms of which remain largely elusive. In this study, personalized dorsal and ventral forebrain organoids (DFOs/VFOs) are generated derived from
Jinhong Xu, Yufei Kong, Nawen Wang, Huijuan Li, Yunteng Li, Zhuo Liu, Yuling Yang, Xiao Yu, Huihui Liu, Jing Ding, Yi Wang, Rui Zhao, Zhicheng Shao   +12 more
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Van der Waals Heterostructures for Next‐Generation Spintronics: Multiferroic‐Mediated Magnetoelectric Properties

Advanced Science, EarlyView.
As CMOS technology approaches fundamental energy limits, new paradigms for low‐power information processing are required. Magnetic systems are attractive for their spin transport, yet current‐induced magnetization control is energy inefficient. Multiferroic heterostructures enable energy‐efficient electric field manipulation of magnetism.
Donghyeon Lee, Jiwoong Yang, Inhyeok Oh, Sanghan Lee   +3 more
wiley   +1 more source