Results 221 to 230 of about 1,472,869 (283)

Single‐Nucleus RNA Sequencing Identifies CREM as a Brake on Myofiber Hypertrophy in Chickens

open access: yesAdvanced Science, EarlyView.
Single‐nucleus RNA sequencing on 91 144 nuclei from postnatal chicken pectoralis major between fast‐growing broilers (FG) and slow‐growing layers (SG) identifies the transcriptional factor CREM as a novel brake of myofiber hypertrophy. Mechanistically, functional validation experiments confirm that CREM activates the promoter of JUN and CREM deletion ...
Shuang Gu   +12 more
wiley   +1 more source

Injectable Peptide‐Based Functional Amyloid Hydrogels as Tunable Depots for Sustained Drug Delivery

open access: yesAdvanced Science, EarlyView.
An injectable and tunable peptide‐based functional amyloid hydrogel provides sustained insulin release while preserving insulin stability and bioactivity. The hydrogel enables prolonged glycemic regulation in vivo, exhibits excellent biocompatibility, and shows no detectable IAPP and α‐Syn heterologous cross‐seeding, highlighting its potential as a ...
Ranjit Shaw   +4 more
wiley   +1 more source

Fully Integrated Wearable Ultrasound System for Continuous Promotion of Wound Healing

open access: yesAdvanced Science, EarlyView.
A wearable ultrasound system integrating a drug‐loaded patch and a miniaturized driving circuit is presented to achieve noninvasive, on‐demand stimulation, enabling programmable antibacterial activity, inflammation modulation, and accelerated wound closure through enhanced cell migration and collagen remodeling.
Faxing Zou   +7 more
wiley   +1 more source

Enhancer binding kinetics explain transcription factor hub formation. [PDF]

open access: yesSci Adv
Fallacaro S   +6 more
europepmc   +1 more source

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