Results 31 to 40 of about 59,148 (256)

Noise-tuned bursting in a Hedgehog burster

open access: yesFrontiers in Computational Neuroscience, 2022
Noise can shape the firing behaviors of neurons. Here, we show that noise acting on the fast variable of the Hedgehog burster can tune the spike counts of bursts via the self-induced stochastic resonance (SISR) phenomenon.
Jinjie Zhu, Jinjie Zhu, Hiroya Nakao
doaj   +1 more source

Mining Bursting Core in Large Temporal Graphs [PDF]

open access: yes, 2023
Temporal graphs are ubiquitous. Mining communities that are bursting in a period of time is essential for seeking real emergency events in temporal graphs.
Qin, L   +5 more
core   +1 more source

RNA Polymerase II cluster dynamics predict mRNA output in living cells

open access: yeseLife, 2016
Protein clustering is a hallmark of genome regulation in mammalian cells. However, the dynamic molecular processes involved make it difficult to correlate clustering with functional consequences in vivo. We developed a live-cell super-resolution approach
Won-Ki Cho   +10 more
doaj   +1 more source

NbO2 Memristive Neurons for Burst‐Based Perceptron

open access: yesAdvanced Intelligent Systems, 2020
Neuromorphic computing using spike‐based learning has broad prospects in reducing computing power. Memristive neurons composed with two locally active memristors have been used to mimic the dynamical behaviors of biological neurons.
Yeheng Bo   +5 more
doaj   +1 more source

Pipe Bursting [PDF]

open access: yes, 2007
Pipe bursting can be used to replace pipes without using open trench methods. Pipe bursting is accomplished by pulling a bursting device through the existing pipe.
ECT Team, Purdue
core   +1 more source

Improving spike sorting performance of bursting neurons [PDF]

open access: yes, 2022
LAUREA MAGISTRALEPer comprendere come le reti neurali crescono, apprendono e sono in grado di svolgere le loro straordinarie funzioni, è fondamentale un metodo affidabile per monitorare la loro attività.
Sadeghi Shabestari, Payam
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

open access: yesFEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto   +14 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Emergent bimodal firing patterns implement different encoding strategies during gamma-band oscillations

open access: yesFrontiers in Computational Neuroscience, 2013
Upon sensory stimulation, primary cortical areas readily engage in narrow-band rhythmic activity between 30 to 90 Hz, the so-called gamma oscillations.
Belén eDe Sancristóbal   +5 more
doaj   +1 more source

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