Results 181 to 190 of about 3,696 (243)

Further observations on trifluperidol: a butyrophenone derivative

Psychopharmacologia, 1965
The experimental butyrophenone compound, trifluperidol, was compared with trifluoperazine and phenobarbital under double-blind conditions in a group of 60 hospitalized chronic schizophrenic patients. Therapeutic response was evaluated by means of 15 quantitative psychiatric, psychologic, and ward behavior measures.
D M, Gallant, M P, Bishop, W M, Nesselhof, D J, Sprehe   +3 more
openaire   +2 more sources

Butyrophenone und strukturanaloge Verbindungen

1998
Trotz einer ahnlichen chemischen Grundstruktur und eines demzufolge ahnlichen Metabolismus verhalten sich die einzelnen Butyrophenone und Diphenylbutylpiperidine bezuglich Adsorption, Verteilung und Elimination sehr unterschiedlich, weitgehend bedingt durch unterschiedlich lipophile Eigenschaften.
K. Heininger, A. Klimke, W. Gaebel, B. Bandelow, E. Rüther, E. Klieser, W. Lemmer   +6 more
openaire   +1 more source

Neuroleptika (Phenothiazine, Butyrophenone)

1992
Zu den Neuroleptika zahlen Phenothiazin- und Butyrophenon-derivate. Ubliche antiemetisch wirksame Einzeldosen von Phenothiazinen wie Chlorpromazin (25–50 mg), Prochlorperazin (5–10–25 mg), Triflupromazin (10–20 mg), Levomepromazin (10–25 mg), Perphenazin (z.B. 5 mg), Fluphenazin (z.B.
openaire   +1 more source

Comparisons between the in vitro binding of two substituted benzamides and two butyrophenones to dopamine-D2 receptors in the rat striatum.

Acta Pharmacologica et Toxicologica, 2009
H. Hall, I. Wedel
semanticscholar   +1 more source

Intramolecular H-atom abstraction in gamma-azido-butyrophenones: formation of 1,5 ketyl iminyl radicals.

Organic Letters, 2009
S. Muthukrishnan, Jagadis Sankaranarayanan, Rodney F. Klima, Tamara C. S. Pace, C. Bohne, A. Gudmundsdottir   +5 more
semanticscholar   +1 more source

Butyrophenones

2005
Jaya Chilakapati, Harihara M. Mehendale
openaire   +2 more sources

New alkylating agents: butyrophenone derivatives.

Anticancer research, 1986
The antimitotic properties associated with the bis (2-chloroethyl) amino group are well known, a number of compounds bearing this group being of therapeutic interest. The choice of a suitable supporting moiety for this group is important. Our experiments on a butyrophenone derivative, ketocaine, which possesses local anesthetic activity, showed that ...
I, Galatulas, A, Andreani, M, Rambaldi, D, Bonazzi, R, Bossa   +4 more
openaire   +1 more source

Anticholinesterase activity of some butyrophenones.

Archives internationales de pharmacodynamie et de therapie, 1978
The anticholinesterase (antiChE) activity of haloperidol, droperidol and trifluperidol was studied by employing dog plasma as a cholinesterase source and changes in arterial blood pressure, elecited by a mixture of acetylcholine (Ach) and dog plasma with or without those drugs, as an indicator of their antiChE activity. When butyrophenones were present
Z B, Fortes, R, Scivoletto, C C, Reis
openaire   +1 more source

DETERMINATION OF pK a VALUES OF SOME BUTYROPHENONES, THEIR SENSITIVE LC-UV ANALYSIS IN PHARMACEUTICAL DOSAGE FORMS AND STRESS DEGRADATION BEHAVIOR UNDER ICH-RECOMMENDED STRESS CONDITIONS

, 2012
S. Şanlı, S. Özkan, Z. Güney
semanticscholar   +1 more source

Inhibition of human erythrocyte Ca++-transport ATPase by phenothiazines and butyrophenones.

Biochemical and Biophysical Research Communications - BBRC, 1980
K. Gietzen, A. Mansard, H. Bader
semanticscholar   +1 more source