General Anesthesia and Altered States of Arousal: A Systems Neuroscience Analysis [PDF]
, 2011 Placing a patient in a state of general anesthesia is crucial for safely and humanely performing most surgical and many nonsurgical procedures. How anesthetic drugs create the state of general anesthesia is considered a major mystery of modern medicine ...
Brown, Emery N. +2 more
core +1 more source
Selektivna i osjetljiva metoda određivanja metoprolola u humanoj plazmi tekućinskom kromatografijom spregnutom s masenom spektrometrijom [PDF]
, 2010 A high-performance liquid chromatography-tandem mass spectrometric method was developed and validated for the determination of metoprolol in human plasma.
Bommana Naresh Kumar +3 more
core +2 more sources
Antipsychotics in the treatment of psychosis: risks and benefits [PDF]
, 2013 Antipsychotics are important in the treatment and recovery of people with psychosis but current evidence suggests that mental health nurses are not always conversant with the risks and benefits of these drugs.
Bressington, D., Mutsatsa, S.
core +1 more source
Effects of neuroleptic butyrophenones on pituitary-adrenal activity in rats.
Journal of Pharmacobio-Dynamics, 1980 T. Aimoto +4 more
semanticscholar +3 more sources
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia [PDF]
, 2018 Background : Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in people with dementia although there is uncertainty about the effectiveness of their long-term use for this indication and concern that they may cause harm ...
Christiaens, Thierry +6 more
core +2 more sources
Light‐Induced On‐Surface Reactions: Bridging Photochemistry and Surface Science
ChemPlusChem, Volume 90, Issue 11, November 10, 2025.This minireview examines molecular on‐surface photochemistry as an emerging strategy for synthesizing carbon‐based nanomaterials on substrates. A special emphasis is placed on bridging traditional photochemistry principles with surface science concepts.
Federico Frezza +3 more
wiley +1 more source
British Journal of Pharmacology, Volume 182, Issue 22, Page 5574-5595, November 2025.Abstract Background and Purpose Pharmacological activation of neuronal M‐current mediated by Kv7 (Kv7.2–5) potassium channels is a validated mechanism for epilepsy treatment. However, since the market withdrawal of the prototype Kv7 activator retigabine, no Kv7 activator is clinically available for this condition.
Lidia Carotenuto +16 more
wiley +1 more source
The Treatment of Alcohol Withdrawal [PDF]
, 1989 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90352/1/j.1875-9114.1989.tb04119.x ...
Guthrie, Sally K.
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Systematic review and meta‐analysis of antipsychotic discontinuation in dementia
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 4, October-December 2025.Abstract INTRODUCTION Antipsychotics are used to treat behavioral and psychological symptoms of dementia (BPSD). However, treatment is associated with adverse outcomes. A 2018 Cochrane review found low‐quality evidence that discontinuation may have little effect on BPSD by primarily comparing the difference in number of study non‐completers between ...
Sophie Roche +5 more
wiley +1 more source
Modular Synthesis of Heterobenzylic Amines via Carbonyl Azinylative Amination
Angewandte Chemie, Volume 136, Issue 42, October 14, 2024.An indium metal‐mediated carbonyl azinylative amination (CAzA) reaction provides an operationally straightforward protocol for the multicomponent coupling carbonyls, amines and 2‐iodo azines to form α‐alkyl, α′‐2‐azinyl amines. This modular reaction displays a broad scope and only a metal reductant is needed to generate a reactive 2‐azinyl nucleophile.
Alex A. Rafaniello +3 more
wiley +2 more sources